摘要
目的探讨躯体化障碍采取小剂量抗精神病药物联合心理疗法的治疗效果。方法选取2019年12月—2020年12月在该院收治的80例躯体化障碍患者作为研究对象,按就诊顺序编号,分为两组,各40例。奇数编号为对照组,偶数编号为观察组。将单纯小剂量抗精神病药物治疗应用于对照组,观察组在此基础上联合心理疗法进行治疗。比较治疗前后的汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、自测健康评定量表(SRHMS)、匹茨堡睡眠质量指数(PSQI)、社会支持评定量表(SSRS)评分以及不良反应发生情况。结果治疗前两组HAMD、HAMA及SRHMS评分差异无统计学意义(P>0.05),经过治疗后,观察组HAMD(38.12±6.13)分、HAMA(35.31±6.02)分明显低于对照组(45.84±6.65)分、(46.45±5.76)分,差异有统计学意义(t=5.397、8.456,P<0.05),观察组SRHMS评分(332.31±41.32分)明显高于对照组(285.42±40.98分),差异有统计学意义(t=5.096,P<0.05)。观察组(12.50%)与对照组(15.00%)的不良反应发生率比较,差异无统计学意义(t=0.105,P=0.745)。结论对躯体化障碍患者采取小剂量抗精神病药物联合心理疗法进行治疗效果理想,有助于改善患者焦虑、抑郁状态,强化自我健康感受,不会导致不良反应发生风险增加,安全性较好,值得临床应用。
Objective To explore the therapeutic effect of low-dose antipsychotics combined with psychotherapy for somatization disorders.Methods Selected 80 patients with somatization disorders admitted to the hospital from December 2019 to December 2020 as the research object.They were numbered according to the order of treatment,and were divided into 2 groups with 40 cases in each group.The odd numbers were the control group,and the even numbers were the observation group.The simple low-dose antipsychotic treatment was applied to the control group,and the observation group was treated with psychotherapy on this basis.Compared the Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA),Self-Tested Health Rating Scale(SRHMS),Pittsburgh Sleep Quality Index(PSQI),Social Support Rating Scale(SSRS)scores and the occurrence of adverse reactions before and after treatment.Results Before treatment,there were no statistically significant differences in HAMD,HAMA and SRHMS scores between the two groups(P<0.05).After treatment,HAMD(38.12±6.13)points and HAMA(35.31±6.02)points scores in the observation group were significantly lower than those in the control group(45.84±6.65)points,(46.45±5.76)points,the difference was statistically significant(t=5.397,8.456,P<0.05).SRHMS score of observation group(332.31±41.32)pointswas significantly higher than that of control group(285.42±40.98)points,the difference was statistically significant(t=5.096,P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the observation group(12.50%)and the control group(15.00%)(t=0.105,P=0.745).Conclusion The treatment effect of low-dose antipsychotics combined with psychotherapy for patients with somatization disorder is ideal,which is helpful to improve patients'anxiety and depression,strengthen their self-health feeling,and will not increase the risk of adverse reactions.It has good safety and is worthy of clinical application.
作者
袁春媛
YUAN Chunyuan(Baicheng Social Psychiatric Hospital,Baicheng,Jilin Province,137000 China)
出处
《世界复合医学》
2021年第10期166-170,共5页
World Journal of Complex Medicine
