摘要
目的:探讨应用洗必泰预防食管癌患者术后呼吸机相关性肺炎(Ventilator-associated pneumonia,VAP)的临床效果。方法:选择2018年11月—2020年5月就诊于我院心胸外科需行根治性手术的食管癌120例,按患者入院顺序编号,参照随机数字表分为实验组和对照组,各60例。实验组采用复方洗必泰含漱液清洁口腔;对照组则采用生理盐水清洁口腔。比较两组患者口腔的细菌检出情况和呼吸机相关性肺炎(VAP)发生率。结果:实验组患者口腔阳性菌检出率、口腔异味、牙龈肿胀、口腔溃疡和VAP发生率均为0(0.0%);对照组口腔阳性菌检出率为8例,检出率为13.3%,口腔异味发生率为13.3%,牙龈肿胀发生率为8.3%,口腔溃疡发生率为10.0%;实验组平均住院时间为(14.32±3.81)d,对照组平均住院时间为(18.89±3.73)d;实验组未发生VAP,对照组VAP发生6例,发生率为10.0%,差异均有统计学意义(P<0.05)。结论:患者手术前采用复方洗必泰口腔漱口液能有效降低口腔菌落数,抑制口腔内的细菌,减少口腔细菌定植,对降低术后VAP的发生率有良好的效果。操作简单、效果明显。
Objective:To investigate the clinical effect of Xibitai in the prevention of postoperative ventilator-associated pneumonia(VAP)in patients with esophageal cancer.Methods:A total of 120 cases of esophageal cancer needing radical surgery were selected for treatment in the cardiothoracic surgery department of our hospital from November 2018 to May 2020.The patients were numbered according to the admission sequence,and randomly divided into the experimental group and the control group randomly,with 60 cases in each group.Compound chlorhexidine gargle was used to clean the oral cavity in the experimental group.The control group received saline to clean the mouth.The oral bacterial detection and incidence of ventilator-associated pneumonia(VAP)were compared between the two groups.Results:The positive oral detection rate,the incidence of oral odor,the gingival swelling,the oral ulcer and VAP incidence in the experimental group were 0(0.0%).In the control group,the positive oral cavity detection rate was 8 cases(13.3%);the incidence of oral odor was 13.3%,gingival swelling 8.3%,oral ulcer 10.0%;6 cases(10.0%)with VAP.The average length of stay was(14.32±3.81)days in the experimental group,and(18.89±3.73)days in the control group.The difference between the two groups was statistically significant(P<0.05).Conclusion:Before the operation,the patients were treated with compound chlorphenicol oral rinse solution,which could effectively reduce the number of oral bacteria,inhibit the bacteria in the oral cavity,reduce the fixed value of oral bacteria,and it has a good effect on reducing the incidence of postoperative VAP.It is simple and effective.
作者
侯良
钟美兴
刘华之
陈辉
刘群
HOU Liang;ZHONG Mei-xing;LIU Hua-zhi;CHEN Hui;LIU Qun(Department of Hospital Infection Management,the First Affiliated Hospital of Gannan Medical University;Department of Cardiothoracic Surgery,the First Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi 341000)
出处
《赣南医学院学报》
2021年第11期1111-1113,共3页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
基金
赣州市指导性科技计划项目(GZ2018ZSF108)。
关键词
洗必泰
食管癌手术
呼吸机相关性肺炎
Chlorhexidine
Surgery for esophageal cancer
Ventilator-associated pneumonia
