摘要
目的分析四川省人间布鲁氏菌病(布病)流行病学及临床特征,为布病防控提供科学依据。方法采用回顾性分析方法,收集2018-2020年四川省布病报告病例资料(来源于"中国疾病预防控制信息系统"中的"传染病报告信息管理系统"),对人间布病病例的三间分布情况(人群、时间、地区分布)和个案调查资料(流行病学接触史、临床表现)进行描述性流行病学分析。结果2018-2020年四川省共报告布病病例309例,无死亡病例,年均发病率为0.123/10万。在309例布病报告病例中,男女性别比为2.4∶1.0(218∶91);发病年龄主要集中在20~60岁,占79.9%(247/309);职业以农民为主,占51.8%(160/309)。全年各月均有布病报告病例,主要集中在3-8月,占总病例数的72.5%(224/309)。2018-2020年四川省21个市(自治州)均有布病病例报告,其中累计发病数前5位的市(自治州)依次为成都、凉山、自贡、内江、泸州,合计病例数占总病例数的60.5%(187/309)。在309例布病报告病例中,完成个案调查279例,其中有牲畜及其制品接触史者258例,占92.5%;接触牲畜种类均为羊;传播方式主要为直接接触传播,占88.5%(247/279);传播途径主要为养羊(50.2%,140/279)、屠宰羊(18.6%,52/279)、卖羊肉或羊肉餐馆切割羊产品(11.1%,31/279);主要临床表现为发热、乏力、多汗和肌肉及关节酸痛,分别占91.4%(255/279)、89.2%(249/279)、80.3%(224/279)和65.2%(182/279)。结论四川省布病疫情呈扩散加重趋势,春夏季流行。布病病例以散养羊农户高发,直接接触感染为主;临床表现多样但无特异性。相关部门应加强针对重点人群和地区的防控工作,以控制布病疫情发生。
Objective To analyze the epidemiological and clinical characteristics of human brucellosis in Sichuan Province,and to provide a scientific basis for prevention and control of brucellosis.Methods Retrospective analysis methods were used to collect the data of reported cases of brucellosis in Sichuan Province from 2018 to 2020 from the"Infectious Disease Reporting Information Management System"in the"China Disease Prevention and Control Information System".The distribution(population,time and region)and case investigation data(epidemiological contact history and clinical manifestations)were analyzed by descriptive epidemiological.Results A total of 309 cases of brucellosis were reported in Sichuan Province in 2018-2020,and no deaths occurred.The annual incidence rate was 0.123/100000.Among the 309 reported cases of brucellosis,the sex ratio of men to women was 2.4∶1.0(218∶91);the age of onset was mainly 20-60 years old,accounting for 79.9%(247/309);the occupation was mainly farmers,accounting for 51.8%(160/309).Brucellosis cases were reported in every month of the year,mainly from March to August,accounting for 72.5%(224/309)of the total number of cases.Cases were reported in 21 cities(autonomous prefectures)in Sichuan Province from 2018 to 2020.The top 5 cities(autonomous prefectures)in terms of cumulative number of cases were Chengdu,Liangshan,Zigong,Neijiang and Luzhou in order,accounting for 60.5%(187/309)of the total number of cases.Among the 309 reported cases of brucellosis,279 case investigations were completed.Among them,258 cases had a history of contact with livestock and their products,accounting for 92.5%;all contacted livestock were sheep;the main mode of transmission was direct contact,accounting for 88.5%(247/279);the main routes of transmission were sheep farming(50.2%,140/279),sheep slaughtering(18.6%,52/279),selling mutton or cutting sheep products in mutton restaurants(11.1%,31/279);the main clinical manifestations were fever,fatigue,hyperhidrosis,and muscle and joint pain,accounting for 91.
作者
罗春花
刘思彤
袁珩
汪立茂
李帆
吴朝学
刘伦光
Luo Chunhua;Liu Sitong;Yuan Heng;Wang Limao;Li Fan;Wu Chaoxue;Liu Lunguang(Department for Acute Infectious Disease Control and Prevention,Sichuan Provincial Center for Disease Control and Prevention,Chengdu 610041,China;School of Public Health,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China)
出处
《中华地方病学杂志》
CAS
北大核心
2021年第11期923-926,共4页
Chinese Journal of Endemiology
关键词
布鲁氏菌病
流行特征
临床表现
Brucellosis
Epidemiological characteristic
Clinical manifestations
