摘要
目的研究T_(4)期胃癌患者腹腔镜根治术后远期预后的影响因素。方法回顾性分析2016年1月至2017年12月神木市医院收治的50例行腹腔镜根治术治疗的T_(4)期胃癌患者的临床资料。所有患者均行腹腔镜根治术治疗,统计患者一般资料,分析患者随访期间预后情况,采用多因素Logistic回归分析法分析T_(4)期胃癌患者腹腔镜根治术后远期预后的独立影响因素。结果50例患者随访期间,无事件生存31例,占62.00%,复发5例,占10.00%,死亡14例,占28.00%;单因素分析结果显示,T_(4)期胃癌患者腹腔镜根治术后远期预后与肿瘤大小、肿瘤N分期、淋巴结转移及血小板计数有明显相关性(P<0.05);多因素Logistic回归分析显示,淋巴结转移(OR=1.269,95%CI=1.136~1.547)及血小板计数(OR=3.927,95%CI=1.537~2.658)是T_(4)期胃癌患者腹腔镜根治术后远期预后的独立影响因素(P<0.05)。结论淋巴结转移及血小板计数是T_(4)期胃癌患者腹腔镜根治术后远期预后的独立影响因素。
Objective To study the influencing factors of long-term prognosis in patients with T_(4)gastric cancer after laparoscopic radical operation.Methods The clinical data of 50 patients with T_(4)gastric cancer treated by laparoscopic radical gastrectomy in Shenmu Hospital from January 2016 to December 2017 were analyzed retrospectively.All patients were treated with laparoscopic radical surgery,and the general data of patients were analyzed.The prognosis of patients during follow-up was analyzed,and the independent influencing factors of long-term prognosis of T_(4)gastric cancer patients were analyzed by multivariate logistic regression analysis.Results During the follow-up period,31 of the50 patients(62.00%)survived(event-free survival),5 had recurrence(10.00%),and 14 died(28.00%).Univariate analysis showed that long-term prognosis of patients with T_(4)stage gastric cancer after laparoscopic radical resection was significantly correlated with tumor size,tumor N stage,lymph node metastasis,and platelet count(P<0.05).Multivariate logistic regression analysis showed that lymph node metastasis(OR=1.269,95%CI=1.136 to 1.547)and platelet count(OR=3.927,95%CI=1.537 to 2.658)were independent factors for the long-term prognosis of T_(4)gastric cancer patients after laparoscopic radical surgery.Conclusion Lymph node metastasis and platelet count were independent factors influencing the long-term prognosis of patients with T_(4)gastric cancer after laparoscopic surgery.
作者
温陈
遆军锋
张小云
WEN Chen;XI Jun-feng;ZHANG Xiao-yun(Department of Hepatobiliary Surgery,Shenmu Hospital,Shenmu 719300,Shaanxi,CHINA)
出处
《海南医学》
CAS
2021年第23期3076-3078,共3页
Hainan Medical Journal
基金
陕西省自然科学基础研究计划项目(编号:2019JM-496)。
关键词
胃癌
腹腔镜根治术
预后
影响因素
多因素LOGISTIC回归分析
Gastric cancer
Laparoscopic radical operation
Prognosis
Influence factor
Multivariate logistic regression analysis
