摘要
脓毒症是临床上较常见的危重症,也是重症监护室患者常见的并发症和死因,具有病情凶险、发展迅速和病死率高的特点。如何治疗脓毒症以改善患者预后及生存质量十分重要,及时合理的抗感染是脓毒症治疗的重要环节。该文就成人脓毒症患者抗感染治疗的研究进展进行综述,从经验性抗感染、降钙素原指导抗感染、细菌培养联合药敏试验指导抗感染和抗菌肽抗感染展开,旨在为成人脓毒症的抗感染治疗提供一定的依据和参考。
Sepsis is not only a common critical disease,but also a common complication and cause of death of patients in intensive care unit.It has the characteristics of dangerous condition,rapid development and high mortality.How to treat sepsis to improve the prognosis and quality of life of patients is very important.Timely and reasonable antiinfection is a vatal part in the treatment of sepsis.This article will review the progress of anti-infective therapy in adult patients with sepsis,starting from empirical anti-infection,procalcitonin-guided anti-infection,bacterial culture combined drug sensitivity test-guided anti-infection and anti-infection with antimicrobial peptides,aiming to provide a certain basis and reference for the anti-infective treatment of adult sepsis.
作者
沈艺宏
杨卓
刘世平
SHEN Yihong;YANG Zhuo;LIU Shiping(Department of Emergency Medicine,Affiliated Hospital of North Sichuan Medical College,Nanchang,Sichuan 637000,P.R.China)
出处
《华西医学》
CAS
2021年第11期1598-1602,共5页
West China Medical Journal
基金
四川省卫生和计划生育委员会重点研究项目(17ZD016)。
关键词
脓毒症
抗感染
成人
进展
Sepsis
Anti-infection
Adult
Progress
