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远端胃切除术与全胃切除术对胃癌患者术后生存情况的影响分析

Analysis of the effect of distal gastrectomy and total gastrectomy on postoperative survival of patients with gastric cancer
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摘要 目的探讨远端胃切除术与全胃切除术对胃癌患者术后生存情况的影响。方法60例胃癌患者,按照随机数字表法分为远端胃切除术组和全胃切除术组,各30例。远端胃切除术组行远端胃切除术,全胃切除术组行全胃切除术。比较两组患者手术指标、术后住院时间、术后并发症发生情况以及远期生存率、生存质量评分。结果远端胃切除术组患者的手术时间(186.53±50.32)min、术后住院时间(10.68±1.25)d均短于全胃切除术组的(237.65±54.31)min、(12.42±1.34)d,术中出血量(196.54±68.49)ml及淋巴结清扫数量(20.32±6.54)个均少于全胃切除术组的(257.35±70.16)ml、(23.86±6.48)个,差异均具有统计学意义(P<0.05)。远端胃切除术组术后并发症发生率13.33%与全胃切除术组的26.67%比较,差异无统计学意义(P>0.05)。远端胃切除术组患者术后1年后生存率93.33%和术后2年后生存率83.33%均高于全胃切除术组的73.33%、60.00%,差异均具有统计学意义(P<0.05)。远端胃切除术组患者术后1年和术后2年的消化病生存质量指数(GLQI)评分分别为(118.32±10.64)、(98.43±6.54)分,均高于全胃切除术组的(102.37±4.35)、(76.31±5.37)分,差异均具有统计学意义(P<0.05)。结论在胃癌患者的治疗中应用远端胃切除术,术后并发症情况与全胃切除术相当,但患者术后生存率与生存质量高于全胃切除术。因此在胃癌患者的治疗中推荐应用远端胃切除术,可延长患者生存时间。 Objective To discuss the effect of distal gastrectomy and total gastrectomy on postoperative survival of patients with gastric cancer.Methods A total of 60 patients with gastric cancer were divided into distal gastrectomy group and total gastrectomy group according to random numerical table,with 30 cases in each group.The distal gastrectomy group underwent distal gastrectomy,and the total gastrectomy group underwent total gastrectomy.Both groups were compared in terms of surgical indicators,postoperative hospitalization time,postoperative complications,long-term survival rate and quality of life score.Results The operation time(186.53±50.32)min and postoperative hospitalization time(10.68±1.25)d of the distal gastrectomy group were shorter than(237.65±54.31)min and(12.42±1.34)d of the total gastrectomy group,and the intraoperative blood loss(196.54±68.49)ml and number of lymph node dissections(20.32±6.54)nodes were less than(257.35±70.16)ml and(23.86±6.48)nodes of the total gastrectomy group.All the differences were statistically significant(P<0.05).The postoperative complication rate 13.33%in the distal gastrectomy group was not statistically significant when compared with 26.67%in the total gastrectomy group(P>0.05).The survival rates of the distal gastrectomy group were 93.33%at 1 year postoperatively and 83.33%at 2 years postoperatively,which were higher than 73.33%and 60.00%of the total gastrectomy group,and the differences were statistically significant(P<0.05).The gastrointestinal life quality index(GLQI)scores of the distal gastrectomy group were(118.32±10.64)and(98.43±6.54)points at 1 and 2 years postoperatively,which were higher than(102.37±4.35)and(76.31±5.37)points of the total gastrectomy group,and the difference was statistically significant(P<0.05).Conclusion When distal gastrectomy is applied in the treatment of gastric cancer patients,the postoperative complications are comparable to that of total gastrectomy,but the postoperative survival rate and quality of survival of patients are
作者 刘军 LIU Jun(Department of General Surgery,Xinghua Third People’s Hospital,Xinghua 225700,China)
出处 《中国实用医药》 2021年第32期35-37,共3页 China Practical Medicine
关键词 远端胃切除术 全胃切除术 胃癌 生存率 生存质量 Distal gastrectomy Total gastrectomy Gastric cancer Survival rate Quality of life
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