摘要
抑郁症是一种严重危害人体健康的精神心理障碍性疾病,其发病机制比较复杂。近年来,随着对肠道菌群作用研究的不断深入,发现了与抑郁症相关的大脑、胃肠道、微生物菌群之间存在复杂网络关系的脑-肠-微生物轴,它作为一种双向信息调节通路,在人体健康和抑郁症患者防治过程中发挥了重要作用。鉴于此,文章基于脑-肠-微生物轴探讨了肠道菌群影响抑郁症相关研究进展,并讨论了肠道菌群作用下抑郁症未来的防治方向,旨在为抑郁症的治疗提供新思路。
Depression is a mental disorder that seriously endangers human health,its pathogenesis is more complex.In recent years,with the deepening of the research on intestinal flora,found the brain associated with depression,gastrointestinal tract,there is a complex network relationship between brain-gut-microorganism axis,it as a two-way information regulation pathway,in the process of human health and prevention of depression has played an important role.In view of this,this paper,based on the brain-enter-microbe axis,discussed the research progress on the influence of intestinal flora on depression,and discussed the future prevention and treatment of depression under the action of intestinal flora,in order to provide a new research idea for the treatment of depression.
作者
刘保光
董颖
谢苗
刘雅琳
白明
陈毅恒
闫向丽
尚立芝
许二平
LIU Bao-guang;DONG Ying;XIE Miao;LIU Ya-lin;BAI Ming;CHEN Yi-heng;YAN Xiang-li;SHANG Li-zhi;XU Er-ping(Henan University of Chinese Medicine,Zhengzhou 450046,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2021年第10期6027-6029,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(No.81973739)
河南省博士后科研项目(No.19030075)
河南省中医药科学研究专项课题(No.2019ZY1019,No.20-21ZY2144)
河南中医药大学科研启动基金(No.RSBSJJ2018-11)。
关键词
肠道菌群
脑-肠-微生物轴
抑郁症
Intestinal flora
Brain-gut-microorganism axis
Depression
