摘要
目的探讨不同方案预防产妇剖宫产术后出血的应用效果。方法选择2018年3月至2020年3月我院收治的98例剖宫产产妇,采用交替分组法分为观察组(49例)和对照组(49例)。对照组采用缩宫素,观察组采用缩宫素联合米索前列醇。对比两组产妇产后2 h、24 h出血量,凝血功能指标[凝血酶原时间(PT)、纤维蛋白原(FIB)]及不良反应发生率。结果观察组产后2 h、24 h出血量低于对照组(P<0.05)。治疗后,两组的PT缩短,FIB水平降低,且观察组的PT短于对照组,FIB水平低于对照组(P<0.05)。两组的不良反应发生率比较差异无统计学意义(P>0.05)。结论缩宫素联合米索前列醇可有效改善剖宫产产妇的凝血功能,减少术后出血量,且安全性较高。
Objective To explore the application effects of different schemes to prevent bleeding after cesarean section of puerperae.Methods 98 puerperae with cesarean section admitted to our hospital from March 2018 to March 2020 were selected and divided into observation group(49 cases)and control group(49 cases)by alternate grouping method.The control group was treated with oxytocin,and the observation group was treated with oxytocin combined with misoprostol.The blood loss at 2 hours and 24 hours after delivery,blood coagulation function indicators[prothrombin time(PT),fibrinogen(FIB)],and the incidence of adverse reactions were compared between the two groups.Results The blood loss at 2 hours and 24 hours after delivery of the observation group were less than those in the control group(P<0.05).After treatment,the PT and FIB levels of the two groups decreased(P<0.05);The PT of the observation group was shorter than that of the control group,and the FIB level was lower than that of the control group(P<0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Oxytocin combined with misoprostol can effectively improve the blood coagulation function of puerperae with cesarean section,and reduce postoperative blood loss,with higher safety.
作者
李秀眉
陈卫东
熊雪梅
LI Xiumei;CHEN Weidong;XIONG Xuemei(Department of Obstetrics and Gynecology,Meizhou Second Hospital of Traditional Chinese Medicine,Meizhou 514000,China)
出处
《临床医学工程》
2021年第11期1499-1500,共2页
Clinical Medicine & Engineering
基金
梅州市科技计划项目(项目编号:NO.2019B100)。
关键词
剖宫产
出血
缩宫素
米索前列醇
Cesarean section
Bleeding
Oxytocin
Misoprostol
