摘要
目的基于"治未病"理论,探讨中医药预防结肠息肉术后复发的组方用药规律,为结肠息肉的临床治疗提供新思路新方法。方法整理收集近20年国内公开发表的对预防结肠息肉术后复发具有明确疗效的文献,利用SPSS 23.0、SPSS Modeler 18.0进行数据统计分析与挖掘,总结用药频次、性味、归经、分析药物相关性及聚类情况。结果共纳入29篇文献,得到中药预防结肠息肉术后复发方剂33首,涉及中药101味,高频药物27味,使用频率最多的为白术、茯苓、党参、甘草等,得出常用药物组合17组,聚类组方6类。结论中药预防结肠息肉术后复发应以健脾祛湿为核心,兼以清热、理气、活血之法,并可结合现代药理机制灵活配伍应用。
Objective Based on the theory of "preventing disease", to explore the prescription rules of traditional Chinese medicine for preventing postoperative recurrence of colon polyps, and provide new ideas and methods for the clinical treatment of colon polyps. Methods This study searched literature published in China in the past 20 years with clear efficacy in preventing colon polyp recurrence after operation. The drug frequency, tastes, menstruation, correlation and clustering were analyzed by SPSS 23.0 and SPSS Modeler 18.0. Results A total of 29 articles were included, and 33 traditional Chinese medicine prescriptions were obtained to prevent postoperative recurrence of colon polyps, including 101 traditional Chinese medicine prescriptions and 27 high-frequency drugs. The most frequently-used ones were Baizhu(Rhizoma Atractylodis Macrocephalae),Fuling(Poria),Dangshen(Radix Codonopsis),Gaocao(Radix Et Rhizoma Glycyrrhizae), etc. A total of 17 groups of commonly-used drugs were obtained, and 6 groups of cluster prescriptions were obtained. Conclusion To prevent colon polyp recurrence after operation, traditional Chinese medicine should focus on strengthening spleen and clearing damp, and use methods of clearing heat, regulating Qi and promoting blood circulation.
作者
李熠
李琼玉
梁靖华
LI Yi;LI Qiongyu;LIANG Jinghua(Shenzhen Traditional Chinese Medicine Anorectal Hospital(Futian),Shenzhen 518000,Guangdong,China)
出处
《实用中医内科杂志》
2021年第10期36-38,I0009,共4页
Journal of Practical Traditional Chinese Internal Medicine
基金
广东省中医药管理局基金(粤中医办[2020]1)。
关键词
结肠息肉
术后复发
中药
数据挖掘
用药规律
治未病
polyp of colon
postoperative recurrence
traditional Chinese medicine
data mining
using drugs regularity
preventive treatment of disease
