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大肠癌患者肠镜活检组织病理特点分析

Analysis histopathological characteristics of colonoscopy biopsy in patients with colorectal cancer
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摘要 目的对肠镜活检组织病理检查确诊为大肠癌患者的临床病理结果进行分析。方法选取2018年11月-2020年10月天津市南开医院收治的240例经肠镜活检组织病理检查确诊为大肠癌的患者作为研究对象,分析大肠癌患者性别、年龄分布,病理分型,各年龄段的好发部位,了解大肠癌患者的临床病理特点。结果通过240例大肠癌患者的临床病理学分析,平均发病年龄为(65±17)岁,其中>60~80岁发病率最高,为64.58%,与其他年龄段比较,差异均有统计学意义(P<0.05)。直肠的发病率最高为34.58%,然后依次为乙状结肠、升结肠、结肠肝曲、降结肠、回盲部、横结肠、结肠脾曲。>40~60岁患者直肠的发病率最高,与其他年龄段比较,差异均有统计学意义(P<0.05);>80岁患者升结肠的发病率最高,与其他年龄段比较,差异均有统计学意义(P<0.05)。腺癌为大肠癌的主要病理类型占96.67%,然后依次为印戒细胞癌占2.50%、黏液腺癌占0.42%、鳞状细癌占0.42%。结论肠镜活检组织病理检查对于大肠癌具有较高的诊断价值,可鉴别肠癌病灶部位、组织分型,为临床早期诊疗提供较为客观的依据,值得临床推广使用。 Objective To analyze the clinical pathology results of colorectal cancer patients diagnosed by colonoscopy biopsy histopathology. Methods From November 2018 to October 2020,240 patients with colorectal cancer diagnosed by colonoscopy biopsy histopathology were selected as research objects. The gender,age distribution,pathological classification and predisposing sites of patients with colorectal cancer were analyzed to understand the clinicopathological characteristics of patients with colorectal cancer. Results The clinicopathological analysis of 240 patients with colorectal cancer showed that the average onset age was(65±17)years old,and the highest incidence rate was 64.58% at the age of >60-80 years,compared with other age groups,the differences were statistically significant(P<0.05). The highest incidence rate of rectum was 34.58%,followed by sigmoid colon,ascending colon,hepatic flexure,descending colon,ileocecal junction,transverse colon and splenic flexure. The incidence rate of rectum in patients aged >40-60 years was the highest,and the differences were statistically significant compared with other age groups(P<0.05). The incidence rate of ascending colon was higher in patients aged >80 years than in other ages,and the differences were statistically significant compared with other age groups(P<0.05).Adenocarcinoma was the main pathological type of colorectal cancer,accounting for 96.67%,followed by signet ring cell carcinoma,mucinous adenocarcinoma and squamous cell carcinoma,accounting for 2.50%,0.42% and 0.42%,respectively. Conclusion Enteroscopy biopsy histopathology had high diagnostic value for colorectal cancer. It could identify the location and histological classification of colorectal cancer,provide a more objective basis for early clinical diagnosis and treatment,and was worthy of clinical promotion and application.
作者 张玲 ZHANG Ling(Department of Pathology,Tianjin Nankai Hospital,Tianjin 300100,China)
出处 《中国城乡企业卫生》 2021年第10期136-138,共3页 Chinese Journal of Urban and Rural Enterprise Hygiene
关键词 肠镜活检 病理诊断 大肠癌 Colonoscopy biopsy Pathological diagnosis Colorectal cancer
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