摘要
目的探究新生儿感染性肺炎发生及影响因素。方法对河南省新乡市妇幼保健院2018年6月—2020年5月收治的712例新生儿临床资料进行回顾性研究,分析新生儿感染性肺炎的发生情况及影响因素。结果712例新生儿中,发生感染性肺炎的患儿共有71例,发生率9.71%。71例感染性肺炎新生儿中共检出78株病原菌,包括革兰阴性菌(大肠埃希菌、肺炎克雷伯菌等)、革兰阳性菌(金黄色葡萄球菌、表皮葡萄球菌等)、真菌(白色假丝酵母菌)。感染性肺炎新生儿的胎龄<37周、出生体重<1500 g、血清白蛋白<28 g/L、胎膜早破、羊水污染、宫内窘迫、气管插管人数所占比例高于未发生感染性肺炎新生儿,差异有统计学意义(P<0.05)。胎龄<37周、出生体重<1500 g、血清白蛋白<28 g/L、胎膜早破、羊水污染、宫内窘迫与气管插管均是引发感染性肺炎的独立危险因素(P<0.05)。结论革兰阴性菌是本研究引发新生儿感染性肺炎的主要致病菌。导致新生儿发生感染性肺炎的因素相对较多,需要医护人员对相关引发因素予以高度关注。
Objective To explore occurrence and factors of neonatal infectious pneumonia.Methods Clinical data of 712 hospitalized newborns in Xinxiang hospital from June,2018 to May,2020 were reviewed.Results 71 cases of infectious pneumonia occurred among these 712 newborns.Prevalence rate was 9.71%.A total of 78 strains of pathogenic bacteria were detected in those 71 cases,including gram-negative bacteria(Escherichia coli,Klebsiella pneumoniae,etc.),gram-positive bacteria(Staphylococcus aureus,Staphylococcus epidermidis,etc.),fungi(Candida albicans).The percentages of gestational age<37 weeks,birth weight<1500 g,serum albumin<28 g/L,premature rupture of membranes,amniotic fluid contamination,intrauterine distress,and endotracheal intubation were significantly higher among neonates with infectious pneumonia than those without this disease(P<0.05).Gestational age<37 weeks,birth weight<1500 g,serum albumin<28 g/L,premature rupture of membranes,amniotic fluid contamination,intrauterine distress and endotracheal intubation were independent risk factors of infectious pneumonia(P<0.05).Conclusion Gram negative bacteria is the main pathogen causing neonatal infectious pneumonia.Other factors can also lead to neonatal infectious pneumonia,which should be paid close attention by medical staffs.
作者
李娉娉
LI Ping Ping(Xinxiang Maternal and Child Health Care Hospital,Xinxiang 453000,Henan Province,China)
出处
《中国妇幼卫生杂志》
2021年第4期69-72,共4页
Chinese Journal of Women and Children Health
关键词
新生儿
感染性肺炎
病原菌分布
newborn
infectious pneumonia
pathogen distribution
