摘要
目的:化痰行瘀通腑汤联合穴位敷贴治疗慢性阻塞性肺疾病急性加重期(Acute Exacerbation Chronic Obstructive Pulmonary Disease,AECOPD)的临床疗效。方法:选取2015年2月-2020年2月收治的106例AECOPD患者随机分为观察组和对照组,对照组给予常规西药治疗,观察组给予化痰行瘀通腑汤联合穴位敷贴治疗,比较两组临床疗效、治疗前后肺功能、炎性、血气分析指标水平。结果:观察组临床疗效总有效率较对照组显著更高。治疗前两组肺功能、炎性、血气分析指标无显著性差异(P>0.05),治疗后观察组1秒用力呼气肺容积(Forced Expiratory Volume in the First Second,FEV_(1))、第1秒用力呼气容积占预计值百分比(FEV_(1)%)、FEV_(1)/用力肺活量(Forced Vital Capacity,FVC)、白细胞介素-6(Interleukin-6,IL-6)、白三烯B4(Leukotriene B4,LTB4)、肿瘤坏死因子-α(Tumor Necrosis Factor-α,TNF-α)、C反应蛋白(C-reactive Protein,CRP)、氧分压(Partial Pressure of Oxygen,PaO_(2))、二氧化碳分压(Partial Pressure of Carbon Dioxide,PaCO_(2))、血氧饱和度(Oxygen Saturation,SaO_(2))指标改善更显著,差异具有统计学意义(P <0.05)。结论:化痰行瘀通腑汤联合穴位敷贴提高临床疗效,改善肺功能及血气分析,减轻炎症反应。
Objective:To observe clinical efficacy of the Huatan Xingyu Tongfu decoction(化痰行瘀通腑汤) plus acupoint application on AECOPD.Methods:106 cases from February 2015 to February 2020 were randomly divided into two groups.The control group was treated with conventional western medicine,and the observation group was treated with the Huatan Xingyu Tongfu decoction plus acupoint application.Results:The total efficiency in the observation group was significantly higher.After treatment,FEV_(1),FEV_(1)%,FEV_(1)/FVC,IL-6,LTB4,TNF-α,CRP,PaO_(2),PaCO_(2),SaO_(2) index in the observation group improved more significantly(P<0.05).Conclusion:The Tanxingyu Tongfu decoction plus acupoint application on AECOPD can improve clinical efficacy,improve lung function and blood gas analysis,reduce inflammation,and promote patient recovery.
出处
《中医临床研究》
2021年第23期41-43,共3页
Clinical Journal Of Chinese Medicine
关键词
化痰行瘀通腑汤
穴位敷贴
慢性阻塞性肺疾病急性加重期
The Huatan Xingyu Tongfu decoction
Acupoint application
Acute exacerbation of chronic obstructive pulmonary disease
