摘要
目的评价卡前列素氨丁三醇联合低位B-Lynch缝合术治疗前置胎盘性产后出血的可行性和安全性。方法将本院收治的100例产后出血患者按治疗方式分为对照组(缩宫素联合“8”字间断缝合术)和观察组(卡前列素氨丁三醇联合低位B-Lynch缝合术),各50例。比较两组的止血效果、血小板聚集能力、并发症发生情况及生活质量。结果观察组术后2、24 h的出血量均少于对照组,产后24 h的血红蛋白水平高于对照组(P<0.05)。产后24 h,两组的CD62p、PGE_(2)水平及PAgT均升高,6-keto-PGF1α水平均降低,且观察组优于对照组(P<0.05)。观察组的并发症总发生率低于对照组,躯体功能、心理功能、物质生活状态、社会功能评分均高于对照组(P<0.05)。结论卡前列素氨丁三醇联合低位B-Lynch缝合术治疗前置胎盘性产后出血可增强血小板聚集能力,提高止血效果,减少并发症的发生。
Objective To evaluate the feasibility and safety of carboprost tromethamine combined with low B-Lynch suture in the treatment of postpartum hemorrhage with placenta previa.Methods One hundred postpartum hemorrhage patients admitted in our hospital were divided into control group(oxytocin combined with"8"intermittent suture)and observation group(carboprost tromethamine combined with low B-Lynch suture)according to the treatment methods,with 50 cases in each group.The hemostatic effect,platelet aggregation ability,complications and quality of life of the two groups were compared.Results The amount of bleeding in the observation group at 2 and 24 h after operation were less than those in the control group,the hemoglobin level at 24 h postpartum was higher than that in the control group(P<0.05).At 24 h postpartum,the CD62p,PGE_(2) level and PAgT increased and 6-keto-PGF1α level decreased in the two groups,and those in the observation group were better than the control group(P<0.05).The total incidence of complications in the observation group was lower than that in the control group,the scores of physical function,psychological function,material life state and social function were higher than those in the control group(P<0.05).Conclusion Carboprost tromethamine combined with low B-Lynch suture in the treatment of postpartum hemorrhage with placenta previa can enhance the platelet aggregation ability,improve the hemostatic effect,reduce complication.
作者
刘若星
赵荣
LIU Ruoxing;ZHAO Rong(Xingping People's Hospital,Xianyang 713100,China)
出处
《临床医学研究与实践》
2021年第32期152-154,共3页
Clinical Research and Practice
