摘要
目的探讨胃髓系肉瘤的临床与病理学特征、诊断与鉴别诊断、预后及治疗。方法回顾性分析2020年8月16日石河子大学医学院第一附属医院收治的1例髓系肉瘤患者的临床病理学、免疫表型及影像学特点。结果胃切除术后病理诊断为胃小弯恶性肿瘤,结合病史考虑为原始幼稚造血细胞肿瘤——髓系肉瘤,倾向于原始单核细胞肉瘤,肿瘤细胞伴组织单核细胞分化。结论胃髓系肉瘤无特异性临床表现,作为血液系统来源的恶性肿瘤,研究其临床表现、微观形态学特点结合免疫表型将有助于精确诊断,择优选取治疗方案,继而改善患者预后。
Objective To investigate the clinical and pathological features,diagnosis and differential diagnosis,prognosis and treatment of gastric myeloid sarcoma.Methods The clinicopathology,immunophenotype and imaging characteristics in a case of myeloid sarcoma treated in the First Affiliated Hospital of School of Medicine of Shihezi University in August 16,2020 were retrospectively analyzed.Results The pathological diagnosis after gastrectomy was malignant tumor of gastric lesser curvature,which was considered as primitive naive hematopoietic cell tumor-myeloid sarcoma by combining with the disease history,tended to be primitive monocyte sarcomas,and the tumor cells were accompanied by tissue mononuclear cell differentiation.Conclusion Gastric myeloid sarcoma has no specific clinical manifestations.As a malignant tumor originated from blood system,studying its clinical manifestations,microscopic morphological characteristics combined with immunophenotype will help the accurate diagnosis and selection of treatment scheme,thereby improves the patient′s prognosis.
作者
于毅
彭昊
杨志豪
黄红芳
齐伟杰
梁伟华
卢香云
陈云昭
齐妍
崔晓宾
YU Yi;PENG Hao;YANG Zhihao;HUANG Hongfang;QI Weijie;LIANG Weihua;LU Xiangyun;CHEN Yunzhao;QI Yan;CUI Xiaobin(Faculty of Pathology,School of Medicine,Shihezi University/Key Laboratory of Xinjiang Endemic and Ethnic Diseases,Shihezi,Xinjiang 832000,China;Department of Pathology,First Affiliated Hospital,Shihezi,Xinjiang 832000,China;Department of Pathology,Suzhou Hi-Tech Zone Peoples Hospital,Suzhou,Jiangsu 215010,China)
出处
《重庆医学》
CAS
2021年第21期3656-3659,共4页
Chongqing medicine
基金
国家自然科学基金项目(81760436)。
关键词
髓系肉瘤
免疫组织化学
病理特征
鉴别诊断
病例报道
myeloid sarcoma
immunohistochemistry
pathological features
differential diagnosis
case report
