摘要
目的:通过观察十一方药酒涂擦联合艾瑞昔布片治疗膝骨关节炎(KOA)的临床效果,分析其有效性、安全性。方法:纳入100例KOA门诊患者,采取随机数字表法随机分成2组(各50例),A组予十一方药酒涂擦联合艾瑞昔布口服治疗,B组应用艾瑞昔布片口服,观察期为2周,分别于治疗前、治疗后1周、2周3个时段,采用VAS、WOMAC、中医临床症状评分等指标评定疗效。结果:A组有效率为94%,优于B组的86%,差异有统计学意义(P<0.05);治疗1周、2周后,两组在VAS、WOMAC、中医临床症状评分上均优于治疗前,差异有统计学意义(P<0.05),组间比较提示治疗组(A组)较观察组(B组)好,差异有统计学意义(P<0.05)。结论:十一方药酒联合艾瑞昔布片中西医结合治疗KOA患者,较单纯西药疗法疗效更好,值得临床推广应用。
Objective:To observe and analyze the efficacy and safety of combination of Shiyifang medicinal wine rubbing and imrecoxib tablets in treating knee osteoarthritis(KOA). Methods:A total of 100 patients with KOA were randomly divided into 2 groups with 50 patients in each group by random number table method. Patients in group A were treated with Shiyifang medicinal wine combined with imrecoxib tablets, and patients in group B were treated with imrecoxib tablets. The observation course was 2 weeks. The VAS, WOMAC, TCM clinical symptom score were used to evaluate the therapeutic efficacy before treatment, 1 week and 2 weeks after treatment respectively. Results:The effective rate of group A was 94%, which was better than that in group B(86%)(P<0.05). After 1 week and 2 weeks of treatment, the scores of VAS, WOMAC and TCM clinical symptoms scores in group A and B were better than those before treatment(P<0.05), and the ratio between groups indicated that the scores in group A were better than those in group B(P<0.05). Conclusion:Shiyifang medicinal wine rubbing combined with imrecoxib tablets on the treatment of KOA patients is more significant than western medicine therapy alone, and it is worthy for further clinical promotion.
作者
梅其杰
徐文飞
段戡
叶永生
袁长深
郭锦荣
延伟伟
毛德文
姚弘毅
MEI Qijie;XU Wenfei;DUAN Kan;YE Yongsheng;YUAN Changshen;GUO Jinrong;YAN Weiwei;MAO Dewen;YAO Hongyi(The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530023,China;Guangxi University of Traditional Chinese Medicine,Nanning 530200,China;The Hospital of Liyuan Affiliated to Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430077,China.)
出处
《中国中医骨伤科杂志》
CAS
2021年第10期43-46,共4页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金
广西科技重大专项(广西创新驱动发展专项资金项目)(桂科AA17202036)。
关键词
十一方药酒
涂擦
非甾体类抗炎药
骨关节炎
Shiyifang medicated wine
inunction
non-steroidal anti-inflammatory drugs
osteoarthritis
