摘要
近年来,随着材料学的发展,一些纳米材料因其具有良好的理化性质,在各领域的应用中体现出巨大优势。其中,碳纳米管(CNT)是碳的同素异形体,为较常见的碳基纳米材料之一,具有良好的理化及生物学性能,因而受到众多研究者的关注。壳聚糖(CHI)是甲壳素脱乙酰基后的天然生物聚合物,无毒,含有大量的羟基、氨基官能团,在水中很难溶解,但可在酸性溶液中溶解并且能够改善CNT在水溶液中的分散性和生物相容性。因此,许多学者尝试将CNT和CHI结合,制成CNT/CHI复合物,其灵敏度高、稳定性好、制作简单且成本低,是一种新型的生物复合材料,可用于生物医学领域。本文就CNT/CHI复合材料的机械性能、抗菌活性、免疫活性、组织愈合等生物医学方面性能的研究进展做一综述。
In recent years,with the development of materials science,some nanomaterials have shown great advantages in various applications due to their good physical and chemical properties.Among them,carbon nanotube(CNT)is an allotrope of carbon.It is one of the more common carbon-based nanomaterials.Since CNT has good physical,chemical,and biological properties,it has attracted the attention of many researchers.Chitosan(CHI)is a natural biopolymer after the deacetylation of chitin.It is non-toxic and contains a large number of hydroxyl and amino functional groups.CHI is difficult to dissolve in water,but it can be dissolved in acidic solutions and can improve the CNT in aqueous solution,as well as dispersibility and biocompatibility in the medium.Therefore,many scholars have tried to combine CNT and CHI to make a CNT/CHI composite,which has high sensitivity,good stability,simple production,and low cost.As a new type of biocomposite material,CNT/CHI composite can be used in the biomedical field.This article summarizes the recent research progress of CNT/CHI composites with regard to its biomedical properties such as mechanical properties,antibacterial activity,immune activity,and role in tissue healing.
作者
吴宏珊
薛智钧
索来
申静
Wu Hongshan;Xue Zhijun;Suo Lai;Shen Jing(Nankai University,Tianjin 300071,China;Department of International VIP Dental Clinic,Tianjin Stomatological Hospital,Tianjin 300041,China)
出处
《中华临床医师杂志（电子版）》
CAS
北大核心
2021年第7期547-551,共5页
Chinese Journal of Clinicians(Electronic Edition)
基金
天津市口腔医院科研基金(青年项目)(2019BSQN02)。
关键词
碳纳米管
壳聚糖
复合材料
生物医学
Carbon nanotubes
Chitosan
Composite materials
Biomedicine
