摘要
随着动态血压监测的普及,睡眠血压的重要性被日益重视。近20余年来,HOPE研究、Syst-Eur研究、MAPEC研究以及Hygia研究等均表明:相比以往常用的日间血压、办公室血压以及随机血压,睡眠血压对于心血管疾病的发病率及死亡率具有更加重要的意义,是更为有效的预后标志。这些证据提示应更加关注睡眠期的高血压控制。尽管睡眠高血压治疗可有效改善睡眠血压,但其背后有很多潜在问题尚存在争议,尤其对于2型糖尿病、慢性肾脏疾病、睡眠呼吸暂停综合征等患者。现就目前睡眠高血压治疗的研究进展和临床意义进行综述。
With the popularity of ambulatory blood pressure monitoring,more and more attention was paid to asleep blood pressure.In the past 20 years,the HOPE study,the Syst-Eur trial,the MAPEC study and the Hygia chronotherapy trial all showed that the asleep blood pressure is more significant for the morbidity and mortality of cardiovascular diseases and is a more effective prognostic marker compared with the common daytime blood pressure,the office blood pressure and the randomized clinical blood pressure.These evidences suggest that we should pay more attention to the clinical significance of hypertension control during sleep.Although the bedtime hypertension treatment can improve the asleep blood pressure effectively,there are still many potential problems behind it,especially for patients with type 2 diabetes,chronic kidney disease,sleep apnea syndrome and so on.This article reviews the research progress and clinical significance of bedtime hypertension treatment.
作者
贾圣琪
李拥军
田丁元
JIA Shengqi;LI Yongjun;TIAN Dingyuan(The Second Affiliated Hospital of Hebei Medical University,Shijiazhuang 050004,Hebei,China;Zhu Xian Yi Memorial Hospital of Tianjin Medical University,Tianjin 300134,China)
出处
《心血管病学进展》
CAS
2021年第10期916-919,共4页
Advances in Cardiovascular Diseases
关键词
睡眠高血压治疗
睡眠血压
动态血压监测
心血管疾病
Bedtime hypertension treatment
Asleep blood pressure
Ambulatory blood pressure monitoring
Cardiovascular disease
