摘要
目的探究对大体积前列腺增生症患者应用分叶分隔法经尿道等离子双极电切术(PKRP)进行治疗的效果。方法106例大体积前列腺增生症患者,采取随机数字表法分为对照组和研究组,每组53例。对照组应用常规前列腺电切术治疗,研究组应用分叶分隔法PKRP治疗。比较两组治疗前后国际前列腺症状评分量表(IPSS)评分、健康调查简表(SF-36)评分、炎症因子[C反应蛋白(CRP)、白细胞介素-8(IL-8)]水平及术后并发症发生情况。结果治疗后,研究组IPSS评分(7.57±1.29)分明显低于对照组的(10.63±2.87)分,SF-36评分(89.40±11.54)分明显高于对照组的(79.12±10.66)分,差异具有统计学意义(P<0.05)。研究组术后并发症发生率为9.43%,明显低于对照组的30.19%,差异具有统计学意义(P<0.05)。治疗后,研究组CRP、IL-8水平均明显低于对照组,差异具有统计学意义(P<0.05)。结论应用分叶分隔法对大体积前列腺增生症患者行PKRP治疗可以有效促进患者临床症状和炎症反应的改善,提高患者前列腺功能和生活质量,同时术后并发症发生率较低,临床疗效和安全性均较高。
Objective To investigate the effect of transurethral plasmakinetic resection of the prostate(PKPP)in the treatment of massive benign prostatic hyperplasia.Methods A total of 106 patients with massive benign prostatic hyperplasia were randomly divided into control group and research group according to random numerical table,with 53 cases in each group.The control group was treated with conventional prostate resection,and the research group was treated with PKRP with lobular separation.Both groups were compared in terms of international prostate symptom scale(IPSS)scores,36-item short-form of health survey(SF-36)scores,levels of inflammatory factors[C-reactive protein(CRP),interleukin cell-8(IL-8)]before and after treatment and postoperative complications.Results After treatment,IPSS score(7.57±1.29)points of the research group was significantly lower than(10.63±2.87)points of the control group,and SF-36 score(89.40±11.54)points was significantly higher than(79.12±10.66)points of the control group.All the differences were statistically significant(P<0.05).The postoperative complication rate in the research group was 9.43%,which was significantly lower than 30.19%in the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of CRP and IL-8 in the research group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of lobular separation method for PKRP has high clinical efficacy and safety for the treatment of patients with massive benign prostatic hyperplasia,and it can effectively improve the clinical symptoms and inflammatory response of patients,improve the prostate function and quality of life of the patients with low postoperative complication rates.
作者
王相平
纪煜航
郑超
李娜
WANG Xiang-ping;JI Yu-hang;ZHENG Chao(Department of Urology,Dalian Fifth People’s Hospital,Dalian 116021,China)
出处
《中国现代药物应用》
2021年第19期45-47,共3页
Chinese Journal of Modern Drug Application
关键词
分叶分隔法
经尿道等离子双极电切术
大体积前列腺增生症
Lobular separation
Transurethral plasmakinetic resection of the prostate
Massive benign prostatic hyperplasia
