摘要
In most pathology labs,clinicians diagnose diseases by examining tissue slices using a light microscope.This process typically requires clinicians to move the microscope stage to different positions and identify areas of interest that can be further analyzed using a higher magnification objective lens.For proper focusing of the slide,the axial position needs to be constantly adjusted by manually rotating the focus knob.As a result,the reviewing process can be easily disrupted when the clinician bumps the slide to the objective lens or switches to a different objective lens for focusing again.Although it remains the gold standard in diagnosing almost all types of cancers,manual microscopic inspection is,in general,labor-intensive and does not form a streamlined workflow in clinical practice.Furthermore,it is largely based on subjective opinions of clinicians:different clinicians may arrive at different conclusions for the same slide and the same person may give different conclusions at different time points[1].