摘要
以CO_(2)、苯胺及其衍生物、溴代烃为原料,1,8-二氮杂二环十一碳-7-烯(DBU)为活化剂,N,N-二甲基甲酰胺(DMF)为溶剂合成了系列氨基甲酸酯类化合物。以苯胺、1-溴正丁烷和CO_(2)的反应为模板反应,考察了溶剂、初始压力和温度、反应物物质的量比、DBU用量及反应时间对反应的影响,获得的最优反应条件为:苯胺1.0 mmol,1-溴正丁烷2.0 mmol,DBU 2.5 mmol,初始压力0.25 MPa,反应温度70℃,DMF 0.5 mL,反应时间30 min。在最优条件下合成了24个氨基甲酸酯类化合物,收率在38%~91%之间。
A series of carbamate compounds were synthesized from carbon dioxide, aniline and its derivatives and brominated hydrocarbons using 1,8-diazabicycloundec-7-ene(DBU) as active agent,N,N-dimethylformamide(DMF) as solvent. The influences of solvent, initial pressure and temperature,molar ratio of reactants, DBU dosage and reaction time on the reaction were investigated using a template reaction of aniline, 1-bromobutane and carbon dioxide. The optimal reaction conditions were obtained as follows: aniline 1.0 mmol, 1-bromobutane 2.0 mmol, DBU 2.5 mmol, initial pressure 0.25 MPa, reaction temperature 70 ℃, DMF 0.5 m L and reaction time 30 min. Under the optimal conditions, 24 carbamate compounds were synthesized with yields of 38%~91%.
作者
蒋帅
刘春
JIANG Shuai;LIU Chun(State Key Laboratory of Fine Chemicals,Dalian University of Technology,Dalian 116024,Liaoning,China)
出处
《精细化工》
EI
CAS
CSCD
北大核心
2021年第10期2154-2160,共7页
Fine Chemicals
基金
国家自然科学基金(21776036)。
关键词
CO_(2)
氨基甲酸酯
低压
精细化工中间体
碳中和
碳达峰
carbon dioxide
carbamate
low pressure
fine chemical intermediates
carbon neutrality
peak carbon dioxide emissions
