摘要
过敏性鼻炎是临床常见病,发病机制相对复杂,目前在诊断和治疗方面仍有缺陷。miRNA是近年来研究的热点,其在过敏性鼻炎中的研究让我们对疾病有了新的认识。文章主要从固有免疫、适应性免疫及表观遗传学因素等角度总结miRNA与过敏性鼻炎的关系,以期揭示过敏性鼻炎的发病机制。
The pathogenesis of allergic rhinitis,a common clinical disease,is relatively complex,and there are still defects in its diagnosis and treatment.The microRNA has been a research hotspot in recent years,and studies on allergic rhinitis provided a new understanding of the disease.This study summarizes the relationship between microRNA and allergic rhinitis in the perspectives of innate immunity,adaptive immunity,and epigenetic factors,in order to determine its pathogenesis.
作者
王宇婷(综述)
王嘉玺(审校)
WANG Yuting(Overview);WANG Jiaxi(Guidance)(Department of Otorhinolaryngology,Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China)
出处
《山东大学耳鼻喉眼学报》
CAS
2021年第5期98-104,共7页
Journal of Otolaryngology and Ophthalmology of Shandong University
基金
耳鼻喉科十二五重点专科(编号:040203001012)
第六批国家老中医药专家学术经验继承项目(编号:20170615)
国家重点研发计划资助项目(编号:2018YFC1704101)。
