摘要
目的:观察丁苯酞氯化钠注射液联合温针灸治疗进展性脑卒中(PS)的临床疗效。方法:将80例气虚血瘀型PS患者按随机数表法分为研究组与对照组各40例。对照组给予丁苯酞氯化钠治疗,研究组在对照组基础上联合温针灸治疗,均治疗28 d。对比2组治疗前后甘油三酯(TG)、同型半胱氨酸(Hcy)、血管紧张素Ⅱ(ANGⅡ)、脑卒中专用生活质量量表(SS-QOL)评分及不良反应。结果:与同组治疗前比较,治疗后2组TG、ANGⅡ、Hcy水平均降低(P<0.05),SS-QOL各维度评分及总分均升高(P<0.05);与对照组治疗后比较,研究组治疗后TG、ANGⅡ、Hcy水平均较低(P<0.05),SS-QOL各维度评分及总分均较高(P<0.05)。治疗期间,2组总不良反应发生率比较,差异无统计学意义(P>0.05)。结论:丁苯酞氯化钠联合温针灸治疗PS,可有效降低患者脑循环障碍发生风险,改善患者生活质量,且安全性较高。
Objective: To observe the clinical effect of butylphthalide and sodium chloride injection combined with warming-needle moxibustion for progressive stroke(PS). Methods:A total of 80 cases of PS patients of qi deficiency with blood stasis type were divided into the study group and the control group according to the random number table method,40 cases in each group. The control group was treated with butylphthalide and sodium chloride,and the study group was additionally treated with warming-needle moxibustion based on the treatment of the control group. Both groups were treated for 28 days. Triglyceride(TG),homocysteine(Hcy),angiotensin Ⅱ(ANGⅡ) and the scores of Stroke-Specific Quality of Life Scale(SS-QOL) before and after treatment as well as the adverse reactions in the two groups were compared. Results:After treatment,the levels of TG,ANG Ⅱ and Hcy in the two groups were decreased when compared with those before treatment(P<0.05),and the scores of each dimension in SS-QOL and the total scores were increased(P<0.05). After treatment,the levels of TG,ANG Ⅱ and Hcy in the study group were lower than those in the control group(P<0.05),and the score of each dimension in SS-QOL and the total score were higher(P<0.05). During treatment,there was no significant difference being found in the comparison of the total incidences of adverse reactions between the two groups(P>0.05). Conclusion: The therapy of butylphthalide and sodium chloride injection combined with warming-needle moxibustion for PS can effectively reduce the risk of cerebral circulation dysfunction and improve the quality of life of patients,with high safety.
作者
占振瀛
王安荔
王志杰
ZHAN Zhenying;WANG Anli;WANG Zhijie
出处
《新中医》
CAS
2021年第19期173-176,共4页
New Chinese Medicine
关键词
进展性脑卒中
丁苯酞氯化钠
温针灸
微循环障碍
Progressive stroke
Butylphthalide and sodium chloride
Warming-needle moxibustion
Microcirculation disturbance
