摘要
目的探讨非ST段抬高心肌梗死(NSTEMI)患者急诊经皮冠状动脉介入术(PCI)治疗后发生心源性死亡的影响因素。方法回顾性分析2018年6月至2020年6月郑州市第九人民医院收治的86例行急诊PCI治疗的NSTEMI患者的临床资料。术后对所有患者随访6个月,将发生心源性死亡患者纳入发生组,未发生心源性死亡纳入未发生组。统计两组患者临床资料,分析NSTEMI患者急诊PCI治疗后发生心源性死亡的影响因素。结果纳入的86例NSTEMI患者中,随访期间12例(13.95%)发生心源性死亡;两组左心室射血分数(LVEF)、血浆D-二聚体(D-D)、血浆脑钠肽(BNP),血清载脂蛋白A-1(ApoA-1)、白细胞介素-6(IL-6)、尿酸(UA)水平比较,差异有统计学意义(P<0.05);组间其他资料比较,差异未见统计学意义(P>0.05)。经Logistic回归分析显示,LVEF低,血浆D-D、BNP水平高,血清IL-6、UA水平高,血清ApoA-1水平低是NSTEMI患者急诊PCI治疗后发生心源性死亡的影响因素(OR>1,P<0.05)。结论 LVEF低,血浆D-D、BNP水平高,血清IL-6、UA水平高,血清ApoA-1水平低是NSTEMI患者急诊PCI治疗后发生心源性死亡的影响因素。
Objective To investigate the influencing factors of cardiac death in patients with non ST segment elevation myocardial infarction(NSTEMI)after emergency percutaneous coronary intervention(PCI).Methods The clinical data of 86 patients with NSTEMI treated by emergency PCI in Zhengzhou Ninth People’s Hospital from June 2018 to June 2020 were retrospectively analyzed.All patients were followed up for 6 months after operation,and the patients with cardiac death were included in the occurrence group,and no cardiac death was included in the non occurrence group.The clinical data of the two groups were analyzed,and the factors influencing cardiac death after PCI were analyzed.Results The incidence of cardiac death was 13.95%in 12 patients with NSTEMI.There were significant differences in the left ventricular ejection fraction(LVEF),D-Dimer(D-D),plasma brain natriuretic peptide(BNP),serum apolipoprotein A-1(ApoA-1),serum interleukin-6(IL-6),serum uric acid(UA)between the two groups(P>0.05).Logistic regression analysis showed that LVEF was low,plasma D-D,BNP,IL-6 and UA were high,and ApoA-1 level was low,which was the influencing factors of cardiac death in NSTEMI patients after PCI(OR>1,P<0.05).Conclusions Low LVEF,high plasma D-D and BNP levels,high serum IL-6 and UA levels,and low serum ApoA-1 levels are the influencing factors of cardiac death in NSTEMI patients after emergency PCI.
作者
郑增强
赵瑞雪
金晓阳
袁清茹
Zheng Zengqiang;Zhao Ruixue;Jin Xiaoyang;Yuan Qingru(Department of Emergency,Zhengzhou Ninth People’s Hospital,Zhengzhou 450000,China;Department of Neurology,Zhengzhou Ninth People’s Hospital,Zhengzhou 450000,China;Department of Cardiology,Zhengzhou Ninth People’s Hospital,Zhengzhou 450000,China)
出处
《中国实用医刊》
2021年第16期43-46,共4页
Chinese Journal of Practical Medicine
关键词
心肌梗死
非ST段抬高型
急诊经皮冠状动脉介入术
心源性死亡
Myocardial infarction
Non ST segment elevation
Emergency percutaneous coronary intervention
Cardiac death
