摘要
流行病学提示,花生过敏的发生率日益增多,并且通常与严重的过敏反应有关。人体的多种炎症机制参与花生过敏的发生。由于花生与其他成分存在的交叉反应使花生过敏的特异性诊断特别困难,但使用组分诊断可以大大提高诊断水平,特别是可以区分原发性和继发性的花生过敏。目前认为嗜碱性粒细胞活化测试也有助于诊断。在治疗方面,与规避所有坚果相反,目前提出了特异性免疫疗法和在生命早期引入花生的观念。该文综述了关于儿童花生过敏的最新研究进展。
Epidemiology suggests an increasing incidence of peanut allergy and is usually associated with severe allergic reactions.A variety of inflammatory mechanisms are involved in peanut allergy.The specific diagnosis of peanut allergy is particularly difficult due to the co-sensitization between peanut and other components,but the use of component-resolved diagnostic can greatly improve the diagnostic level,especially the distinction between primary and secondary peanut allergy.Basophil activation tests are also thought to be helpful in diagnosis.In terms of treatment,instead of avoiding all nuts,specific immunotherapy and the introduction of peanuts early in life have been proposed.This paper reviews the latest research progress on peanut allergy in children.
作者
袁嘉禧(综述)
鲍一笑(审校)
Yuan Jiaxi;Bao Yixiao(Yangpu Hospital,School of Medicine,Tongji University,Shanghai 200090,China)
出处
《国际儿科学杂志》
2021年第9期610-614,共5页
International Journal of Pediatrics
