摘要
目的研究马来酸曲美布汀与双歧杆菌三联活菌散联用模式在肠易激综合征治疗中的价值。方法选取2015年1月—2020年12月该院接受治疗的肠易激综合征患者68例进行研究,入院随机编码,1~34号患者纳入对照组,给予马来酸曲美布汀治疗,35~68号为观察组,给予马来酸曲美布汀与双歧杆菌三联活菌散联用,评估两组患者单项症状疗效与总疗效,分析治疗效果。结果观察组患者的腹胀、腹泻、腹痛及总分分别为(1.56±0.63)分、(1.62±0.48)分、(1.39±0.68)分、(4.52±1.34)分,与对照组(1.95±0.86)分、(2.13±0.58)分、(1.99±0.67)分及(6.89±1.63)相比,差异有统计学意义(t=2.133、3.950、3.665、6.549,P<0.05);观察组患者的临床治疗有效情况显著优于对照组,差异有统计学意义(Z=2.210,P<0.05)。观察组患者的排便困难、排便不尽、粘液便改善情况分别为61.76%(21/34)、58.82%(20/34)、52.94%(18/34),相比于对照组的85.29%(29/34)、82.35%(28/34)、76.47%(26/34)等指标,观察组明显更优,差异有统计学意义(χ^(2)=4.836、4.533、4.121,P<0.05)。结论采取马来酸曲美布汀与双歧杆菌三联活菌散联用的模式治疗肠易激综合征,可有效改善患者的腹胀、腹泻与腹痛单项临床症状,提高临床治疗效果。
Objective To study the value of combined use of trimebutine maleate and triple viable bifidobacterium powder in the treatment of irritable bowel syndrome.Methods 68 patients with irritable bowel syndrome treated in the hospital from January 2015 to December 2020 were selected for the study,and the admission was randomly coded.Patients 1 to 34 were included in the control group and were given Trimeb maleate.In the treatment group,Nos.35-68 were the observation group.Trimebutine maleate was used in combination with Bifidobacterium triple viable bacteria powder to evaluate the efficacy of individual symptoms and the total efficacy of the two groups of patients,and analyze the therapeutic effect.Results Abdominal distension,diarrhea,abdominal pain and total scores of the observation group were(1.56±0.63)points,(1.62±0.48)points,(1.39±0.68)points,(4.52±1.34)points,and the control group(1.95±0.86)points,(2.13±0.58)points,(1.99±0.67)points and(6.89±1.63)points,the difference were statistically significant(t=2.133,3.950,3.665,6.549,P<0.05).The effectiveness of clinical treatment was significantly better than that of the control group,and the difference was statistically significant(Z=2.210,P<0.05).The patients in the observation group had difficulty in defecation,incomplete defecation,and improvement of mucus and stool,respectively,61.76%(21/34),58.82%(20/34),52.94%(18/34),compared with 85.29%(29/34),82.35%(28/34),76.47%(26/34)in the control group and other indicators,the observation group was significantly better,and the difference was statistically significant(χ^(2)=4.836,4.533,4.121,P<0.05).Conclusion Trimeb maleate combined with Bifidobacterium triple viable bacteria powder in the treatment of irritalde bonel syndrem can effectively improve the individual clinical symptoms of abdominal distension,diarrhea and abdominal pain,and improve the clinical treatment effect.
作者
夏国友
XIA Guoyou(Emergency Department,Yancheng Third People's Hospital,Yancheng,Jiangsu Province,224000 China)
出处
《世界复合医学》
2021年第8期158-161,共4页
World Journal of Complex Medicine
