摘要
2型糖尿病肾病(T2DKD)是2型糖尿病最常见的微血管并发症,T2DKD晚期(G4A3期)后,则见大量蛋白尿的形成和肾功能加速减退。近年来中医药治疗T2DKD晚期体现了良好疗效和独特优势,基于中医理论对T2DKD晚期“瘀毒损络”基本病机的认识,多项临床和基础研究表明,补肾活血降浊法对T2DKD晚期大量蛋白尿和肾脏损伤有显著临床疗效。对本病的临床、实验与药理研究进展进行综述。参考文献35篇。
Type 2 Diabetic Kidney Disease(T2DKD)is the most common microvascular complication of Type 2 Diabetes.A large amount of proteinuria is formed and renal function damage is accelerated during the late T2DKD stage(G4A3).In recent years,traditional Chinese medicine has shown good therapeutic effect and unique advantage in the treatment of late stage T2DKD.Based on TCM understanding of the basic pathogenesis of“Collateral damages by stasis and toxin”in late T2DKD,multiple clinical and basic studies have shown that the method of invigorating kidney,promoting blood circulation and descending turbidity has significant clinical efficacy on advanced proteinuria and renal injury in late T2DKD.This paper aims to summarize its research progress in clinical,experimental and pharmacological aspects to guide the clinical practice.There are 35 references.
作者
田瑞娜
周悦欣
安晓飞
TIAN Ruina;ZHOU Yuexin;AN Xiaofei(Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China;Nanjing University of Chinese Medicine,Nanjing 210029,China)
出处
《山东中医杂志》
2021年第11期1277-1281,共5页
Shandong Journal of Traditional Chinese Medicine
基金
国家自然科学基金项目(编号:81774248)
全国西学中骨干人才培训项目(编号:2019-44)。
关键词
糖尿病肾病
蛋白尿
肾功能
瘀毒损络
补肾活血降浊法
diabetic kidney diseases
proteinuria
kidney function
collateral damages by stasis and toxin
invigorating kidney,promoting blood circulation and descending turbidity
