摘要
目的:分析在布地奈德、特布他林雾化治疗的基础上给予吸入用乙酰半胱氨酸溶液对小儿喘息性支气管肺炎的临床效果。方法:将50例小儿喘息性支气管肺炎患者随机分为对照组(n=25)与观察组(n=25)。两组均给予常规治疗联合布地奈德、特布他林雾化治疗,观察组在此基础上加用吸入用乙酰半胱氨酸溶液雾化吸入。对比两组治疗总有效率、临床症状改善时间、住院时间和药物不良反应情况。结果:观察组治疗总有效率、症状改善时间和住院时间显著优于对照组(均P<0.05)。两组不良反应发生率无统计学差异(P>0.05)。结论:布地奈德、特布他林联合吸入用乙酰半胱氨酸溶液雾化吸入治疗小儿喘息性支气管肺炎的临床效果较好,能够提高小儿患者治疗总有效率,加快小儿患者症状、体征缓解时间,缩短其住院的时间。
Objective:To analyze the clinical effect of acetylcysteine solution for inhalation on asthmatic bronchial trachea pneumonia in children on the basis of treatment with budesonide and terbutaline atomization therapy.Methods:Fifty children with asthmatic bronchial trachea pneumonia were randomly divided into a control group(n=25)and an observation group(n=25).Both groups were given routine treatment combined with budesonide and terbutaline atomization,and then the observation group was given acetylcysteine solution for inhalation atomization besides.The overall response rate and the times for the improvement of clinical signs and symptoms,hospitalization and the incidence of adverse drug reactions were compared between the two groups.Results:The overall response rate and the times for symptom improvement and hospitalization were significantly better in the observation group than the control group(all P<0.05).The comparison of the incidence of adverse reactions in the two groups showed no statistical significance(P>0.05).Conclusion:Nebulized inhalation of budesonide and terbutaline combined with acetylcysteine solution for inhalation for the treatment of pediatric asthmatic bronchial trachea pneumonia has a good clinical effect and can improve the overall response rate,speed up the relief of symptoms and signs and shorten the hospitalization time.
作者
陈思
刘素云
万芳
CHEN Si;LIU Suyun;WAN Fang(Department of Pediatrics,Pingxiang People’s Hospital,Pingxiang 337055,China)
出处
《上海医药》
CAS
2021年第19期19-20,45,共3页
Shanghai Medical & Pharmaceutical Journal
