摘要
在临床上,超过半数的抑郁障碍患者伴有躯体疼痛,而炎性介质在两者共同的病理生理过程中发挥着重要作用.外周细胞因子受到刺激后还可产生其他可通过血脑屏障的炎性介质,从而诱发中枢炎症.现主要阐述抑郁障碍伴躯体疼痛相关的炎性细胞因子的研究进展.
Clinically,more than half of patients with depressive disorder have somatic pain,and inflammatory mediators play an important role in the common pathophysiological process of them.Peripheral cytokines can also produce other inflammatory mediators that can pass through the blood-brain barrier after being stimulated,thus inducing the occurrence of central inflammation.This article mainly describes the research progress of inflammatory cytokines related to depressive disorder with somatic pain.
作者
刘莉
叶兰仙
Liu Li;Ye Lanxian(Department of Mental Healthy the Second Hospital of Lanzhou University,Lanzhou 730030,China)
出处
《神经疾病与精神卫生》
2021年第9期647-651,共5页
Journal of Neuroscience and Mental Health
关键词
抑郁障碍
躯体疼痛
炎症
细胞因子类
综述
Depressive disorder
Somatic pain
Inflammation
Cytokines
Review
