摘要
目的 探讨分析肝炎后肝硬化与酒精合并病毒感染所致肝硬化的临床特点。方法 60例肝硬化患者,其中30例酒精合并病毒感染所致肝硬化患者作为观察组,其余30例肝炎后肝硬化患者作为对照组。比较两组临床症状发生率、并发症发生率、各项生化指标。结果 观察组临床症状发生率63.3%高于对照组的36.7%,差异有统计学意义(P<0.05)。观察组并发症发生率53.33%高于对照组的23.33%,差异有统计学意义(P<0.05)。观察组患者的血清尿酸为(513.2±218.8)μmol/L、总胆固醇为(5.4±1.4)μmol/L、甘油三酯为(2.7±0.4)mmol/L、谷氨酰转肽酶为(328.1±198.2)U/L;对照组者的血清尿酸为(308.2±124.1)μmol/L、总胆固醇为(4.5±0.5)μmol/L、甘油三酯为(1.4±0.2)mmol/L、谷氨酰转肽酶为(105.1±32.2)U/L。观察组患者的血清尿酸、总胆固醇、甘油三酯、谷氨酰转肽酶均高于对照组,差异均有统计学意义(P<0.05)。结论 酒精合并病毒感染所致肝硬化患者在临床上有多种表现,尤其是各项临床症状的发生率以及各项生化指标高于肝炎后肝硬化患者,还容易出现多种并发症,所以需要及早为患者确诊,更快开展治疗,才可以有效控制患者的病情进展。
Objective To discuss the clinical features of post-hepatitis cirrhosis combined with liver cirrhosis due to alcohol and virus infection.Methods Among 60 patients with liver cirrhosis,30 patients with liver cirrhosis caused by alcohol combined with viral infection served as the observation group.The remaining 30 patients with post-hepatitis cirrhosis served as the control group.Both groups were compared in terms of incidence of clinical symptoms,incidence of complications,and various biochemical indicators.Results The incidence of clinical symptoms 63.3%in the observation group was higher than 36.7%in the control group,and the difference was statistically significant(P<0.05).The complication rates 53.33%in the observation group was higher than 23.33%in the control group,and the difference was statistically significant(P<0.05).In the observation group,the serum uric acid was(513.2±218.8)μmol/L,the total cholesterol was(5.4±1.4)μmol/L,the triglycerides was(2.7±0.4)mmol/L,theγ-glutamyl transpeptidase was(328.1±198.2)U/L;in the control group,the serum uric acid was(308.2±124.1)μmol/L,the cholesterol was(4.5±0.5)μmol/L,the triacylglycerol was(1.4±0.2)mmol/L,the glutamate transpeptidase was(105.1±32.2)U/L.The serum uric acid,total cholesterol,triglycerides,and transglutaminase of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).Conclusion Patients with cirrhosis due to alcohol combined with viral infection have a variety of clinical manifestations,especially the incidence of clinical symptoms and biochemical indicators are higher than those of patients with post-hepatitis cirrhosis,and are also prone to a variety of complications.So patients need to be diagnosed early and treated more quickly in order to effectively control the progression of their disease.
作者
黄坚灵
HUANG Jian-ling(People’s Hospital of Gaoming District,Foshan 528500,China)
出处
《中国实用医药》
2021年第28期29-31,共3页
China Practical Medicine
关键词
肝炎后肝硬化
酒精合并病毒感染
肝硬化
临床特征
Post-hepatitis cirrhosis
Alcohol combined with virus infection
Liver cirrhosis
Clinical features
