摘要
目的探究多层螺旋CT(MSCT)三维重建对非小细胞肺癌(NSCLC)患者放疗的指导作用。方法回顾性选取2017年6月至2019年2月我院接受放疗的94例NSCLC患者的诊治资料,根据靶区勾画方法不同分为实验组(64例)和常规组(30例)。放疗前常规组通过二维CT扫描后,实验组先后于二维CT扫描、MSCT三维重建后进行靶区体积(GTV)、计划靶体积(PTV)勾画,并测量靶区横、纵径。比较两组检查后PTV缩小、心脏剂量下降、骨髓量下降幅度,治疗疗效、放疗毒副反应发生情况。结果实验组患者经二维CT扫描、MSCT三维重建,二者的GTV差值、肿瘤横径差值、肿瘤纵径差值依次为(19.63±4.77)cm^(3)、(1.75±0.40)mm、(3.20±0.65)mm。与常规组比较,实验组TV缩小、心脏剂量下降及骨髓量下降幅度显著(P<0.05)。所有患者均顺利完成放疗,实验组、常规组治疗疗效无明显差异(P>0.05),但实验组患者中3级以上血液学毒性、放射性肺炎或肺损伤、体重减少>5%发生率均明显低于对照组(P<0.05)。结论MSCT三维重建可提高NSCLC放疗患者靶区勾画准确性,缩小PTV及减少毒副反应发生,可作为常规CT扫描图像靶区勾画的有力补充。
Objective To investigate the guiding role of multi-slice spiral CT(MSCT)three-dimensional reconstruction on radiotherapy for patients with non-small cell lung cancer(NSCLC).Methods The diagnosis and treatment data of 94 NSCLC patients who underwent radiotherapy in the hospital from June 2017 to February 2019 were retrospectively extracted.They were divided into an experimental group(64 cases)and a routine group(30 cases)according to different target volume delineation methods.before radiotherapy,after the routine group was given a two-dimensional CT scan,the experimental group was delineated the gross target volume(GTV)and planned target volume(PTV)after the two-dimensional CT scan and MSCT three-dimensional reconstruction.The transverse and vertical diameter of target volume was measured.PTV reduction,cardiac dose decrease,bone marrow volume decline,curative effect,the occurrence of radiotherapy side effects after the two examinations were compared between the two groups.Results Two-dimensional CT scan and MSCT three-dimensional reconstruction showed that difference value of GTV,difference value of tumor transverse diameter,and difference value of vertical tumor diameter was(19.63±4.77)cm3,(1.75±0.40)mm,and(3.20±0.65)mm in the experimental group,respectively.Compared to the routine group,the amplitude of PTV reduction,cardiac dose decrease,and bone marrow volume decline were significantly greater in the experimental group(P<0.05).All patients completed radiotherapy.There was no significant difference in curative effect between the experimental group and routine group(P>0.05).However,the incidence of hematologic toxicity at level 3 or above,radiation pneumonitis or lung injury,weight loss greater than 5%in the experimental group was significantly lower than in the control group(P<0.05).Conclusion MSCT three-dimensional reconstruction can improve the accuracy of target volume delineation in NSCLC patients undergoing radiotherapy,reduce PTV and reduce the occurrence of side effects.It can be applied as a powerfu
作者
石江勇
江松
SHI Jiang-yong;JIANG Song(Department of Radiology,Chongqing Ninth People's Hospital,Chongqing 400700;Department of Radiology,Chongqing Ping'an Medical Imaging Diagnostic Center,Chongqing 400010)
出处
《中国CT和MRI杂志》
2021年第11期56-58,共3页
Chinese Journal of CT and MRI
关键词
多层螺旋CT
三维重建
非小细胞肺癌
放疗
Multi-slice Spiral CT
Three-Dimensional Reconstruction
Non-small Cell Lung Cancer
Radiotherapy
