摘要
[目的]探索原发性甲状旁腺功能亢进棕色瘤的影像与临床特点,旨在提高对该病的诊断能力。[方法]回顾性分析经手术证实的5例原发性甲状旁腺功能亢进棕色瘤的临床、生化及影像学资料。[结果]5例行甲状旁腺病变切除术,4例为甲状旁腺腺瘤、1例为异位增生的甲状旁腺。4例出现双肾多发结石,2例出现病理性骨折。5例甲状旁腺素明显升高,平均(1246.58±373.31)pg/ml;血钙水平升高,平均(3.25±0.21)mmol/L;血磷水平降低,平均(0.69±0.12)mmol/L。4例棕色瘤为多发,1例棕色瘤为单发,呈溶骨性骨质破坏,增强后明显强化。[结论]棕色瘤常继发于甲状旁腺腺瘤,其血生化检查和影像具有典型特征。
[Objective] To explore the imaging and clinical features of brown tumor secondary to primary hyperparathyroidism and improve the diagnostic capacity for this disease. [Methods] A retrospective study was done on 5 patients who were definitively diagnosed of brown tumor secondary to primary hyperparathyroidism by surgical treatment and biopsy. The clinical, biochemical and imaging characteristics were summarized. [Results] All the 5 patients had parathyroid lesions resected, which was verified by pathology as parathyroid adenoma in 4 cases, parathyroid hyperplasia in 1 case. Before operation, multiple renal calculi were found in 4 patients, whereas femoral pathological fracture occurred in 2 patients. The parathyroid hormone significantly increased in all the 5 cases, with an average of(1 246.58±373.31)pg/ml, and the serum calcium increased in an average of(3.25±0.21) mmol/L, while the serum phosphorus decreased in an average of(0.69±0.12) mmol/L. Of them, 4 patients had multiple brown tumors, while the remaining one had solitary tumor, which presented osteolytic destruction, and enhanced significantly after enhancement. [Conclusion] Brown tumor often occurs secondary to parathyroid adenoma with characteristic variations in blood biochemical tests, and on radiographs.
作者
赵红金
杨慧
郭秀程
李强
ZHAO Hong-jin;YANG Hui;GUO Xiu-cheng;LI Qiang(The Second Affiliated Hospital,Shandong First Medical University,Taian 271000,China)
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2021年第17期1615-1617,共3页
Orthopedic Journal of China
关键词
棕色瘤
影像特点
血生化
临床治疗
brown tumor
imaging features
blood biochemistry
clinical treatment
