摘要
根治性膀胱切除术联合尿流改道是治疗肌层浸润性和高危非肌层浸润性膀胱癌的标准治疗方法。随着手术经验的积累、手术技术的推广和围手术期护理的改进,肠代原位新膀胱通常是外科医生和大容量中心患者的首选尿流改道术式。然而,输尿管肠吻合口狭窄是原位新膀胱术后较为棘手的长期并发症,严重的吻合口狭窄会使肾小球滤过率恶化,最终导致部分或全部永久性肾功能丧失。本文就原位新膀胱术后输尿管肠吻合口狭窄的发生发展、预防及治疗措施进行综述,优化新膀胱术后输尿管肠吻合口狭窄的临床诊疗决策。
Radical cystectomy combined with urinary diversion is the standard treatment for muscle invasive and high-risk non-muscle invasive bladder cancer.With the increase of experience,promotion of surgical techniques and improvement of perioperative nursing,intestinal neobladder has become the first choice for surgeons and patients in large volume centers.However,ureteroenteral anastomotic stricture is a long-term complication after orthotopic neobladder surgery.Severe anastomotic stricture can worsen glomerular filtration rate and eventually lead to partial or total permanent loss of renal function.This article reviews the development,prevention and treatment of ureterojejunostomy stricture after orthotopic neobladder surgery,so as to optimize its clinical diagnosis and treatment.
作者
李云云
韦海荣
栾婷
王海峰
王剑松
LI Yunyun;WEI Hairong;LUAN Ting;WANG Haifeng;WANG Jiansong(Department of Urology,Second Affiliated Hospital of Kunming Medical University,Yunnan Institute of Urology,Kunming 650101,China)
出处
《现代泌尿外科杂志》
CAS
2021年第9期793-797,共5页
Journal of Modern Urology
基金
国家自然科学基金资助项目(No.81660423、81860452)
云南省高校科技创新团队项目资助(No.云教[2019]58号)
昆明医科大学第二附属医院院内科技计划项目任务书(No.2019yk003)。
关键词
原位新膀胱术
输尿管肠吻合口狭窄
危险因素
临床影响
诊断
治疗
orthotopic neobladder
stricture of ureterojejunostomy
risk factors
clinical impact
diagnosis
treatment
