摘要
猪肺炎支原体是引起猪地方性肺炎的主要病原,流行于世界各地,给养猪业造成重大经济损失。本文综述了猪肺炎支原体的主要传播途径以及引起的临床症状和肺部病变,总结了其主要致病机理,分析了综合控制该疫病的方法。猪肺炎支原体的主要传播途径是与感染猪密切接触,也可通过空气远距离传播,但无垂直传播相关报道;猪肺炎支原体感染的主要临床特征是间歇性、强度可变的干咳,但在与其他病原继发或混合感染后,临床症状和肺部病变可能会加重;猪肺炎支原体主要通过释放黏附素引起纤毛发生病变、死亡,导致上皮细胞受损或脱落从而影响纤毛功能,也能通过产生剧毒的H2O2等代谢产物引发毒性效应;防治该病首先要通过生物安全措施控制猪肺炎支原体的传入,其次是采用抗菌药物进行治疗,最后是通过接种疫苗降低其传播率。本文为猪养殖场做好猪肺炎支原体病防控提供了参考。
Mycoplasma hyopneumoniae(MHP),a primary pathogen leading to porcine enzootic pneumonia,has been widely spreading all over the world,causing huge economic losses to pig industry.In the paper,the main spreading routes of MHP,clinical symptoms and pulmonary lesions caused therefrom were reviewed,its major pathogenesis was summarized and the methods to comprehensively control it were analyzed.MHP could spread via close contact with infected pigs,and air for a long distance,but no vertical spreading had been reported;main clinical symptoms included intermittent dry cough with variable intensity,which might be more serious in the event of any secondary or mixed infection with other pathogens.The cilia got diseased or died due to the adhesion released by MHP,which made epithelial cells damaged or exfoliated and subsequently affected the function of cilia,and toxic effects might be produced by metabolites such as virulent H202.To prevent and eradicate the disease,any introduction of MHP should be firstly controlled by bio-safety measures,followed by administration with antibiotics,then reduction of spreading rate through vaccination.A reference was provided in the paper for better prevention and control of MHP in farms.
作者
于海涛
孟信淳
陈玉霞
Yu Haitao;Meng Xinchun;Chen Yuxia(Qingdao Yebio Biological Engineering Co.,Ltd.,Qingdao,Shandong 266114,China)
出处
《中国动物检疫》
CAS
2021年第10期83-86,131,共5页
China Animal Health Inspection
关键词
猪肺炎支原体
流行病学
防控
Mycoplasma hyopneumoniae(MHP)
epidemiology
prevention and control
