摘要
目的探讨气管支气管异物致患儿下呼吸道感染的危险因素。方法回顾性分析2017年5月至2019年3月于徐州医科大学附属徐州儿童医院就诊的气管支气管异物吸入患儿共108例,根据是否发生呼吸道感染将入组患儿分为感染组(51例)和未感染组(57例)。采用Pearson卡方检验或Fisher确切概率法和多因素Logistic回归分析气管支气管异物患儿下呼吸道感染的危险因素。结果感染组和未感染组患儿年龄<2岁(χ^(2)=18.091、P<0.001)、异物类型(χ^(2)=8.731、P<0.001)、异物形状(χ^(2)=12.350、P<0.001)、异物停留时间≥7 d(χ^(2)=7.347、P=0.001)差异均有统计学意义;而性别分布(χ^(2)=0.578、P=0.155)、异物位置(χ^(2)=0.249、P=0.642)、三凹征(χ^(2)=0.636、P=0.127)和肺气肿发生率(χ^(2)=0.076、P=1.289)差异均无统计学意义。多因素Logistic回归分析显示,年龄(<2岁)(OR=4.456,95%CI:2.030~6.883、P<0.001),植物异物(OR=2.685、95%CI:1.576~3.451、P<0.001),非光滑异物(OR=1.648、95%CI:1.436~3.662、P=0.007)和异物停留时间(≥7 d)(OR=1.750、95%CI:1.328~3.553、P=0.003)均为气管支气管异物患儿下呼吸道感染的危险因素。与未感染组相比,感染组患儿的住院时间[(3.9±0.7)d]和抗菌药物使用时间[(7.1±0.3)d]更长,差异均具有统计学意义(t=28.923、P<0.001,t=163.79、P<0.001)。结论年龄<2岁、植物异物、非光滑异物和停留时间≥7 d均为儿童气管支气管异物下呼吸道感染的危险因素,监测这些危险因素有助于评估患儿气管支气管异物的病情,改善其预后。
Objective To investigate the risk factors of lower respiratory tract infection of children with foreign bodies of trachea and bronchus.Methods Clinical data of 108 children with tracheobronchial foreign bodies admitted to Xuzhou Children’s Hospital affiliated to Xuzhou Medical University from May 2017 to March 2019 were analyzed,retrospectively.All children were divided into infection group(51 cases)and non-infection group(57 cases)according to with lower respiratory tract infection or not.The risk factors of lower respiratory tract infection in children with tracheobronchial foreign body were analyzed by chi-square test or Fisher exact probability method and Logistic multivariate regression analysis.Results Age(<2 years old)(χ^(2)=18.091,P<0.001),type of foreign body(χ^(2)=8.731,P<0.001),shape of foreign body(χ^(2)=12.350,P<0.001),foreign body retention time(≥7 d)(χ^(2)=7.347,P=0.001)were all significantly different between the cases of infection group and non-infection group;but gender(χ^(2)=0.578,P=0.155),foreign body location(χ^(2)=0.249,P=0.642),incidences of three concave sign(χ^(2)=0.636,P=0.127)and emphysema(χ^(2)=0.076,P=1.289)were without significant differences.Logistic multivariate regression analysis showed that age(<2 years old)(OR=4.456,95%CI:2.030-6.883,P<0.001),plant foreign body(OR=2.685,95%CI:1.576-3.451,P<0.001),non-smooth foreign body(OR=1.648,95%CI:1.436-3.662,P=0.007)and foreign body residence time(≥7 days)(OR=1.750,95%CI:1.328-3.553,P=0.003)were all risk factors of lower respiratory tract infection.Compared with children of non-infection group,the cases of infection group had longer length of hospitalization[(3.9±0.7)days]and antibiotic application time[(7.1±0.3)days],with significant differences(t=28.923,P<0.001;t=163.79,P<0.001).Conclusions Age<2 years old,plant foreign bodies,non-smooth foreign bodies and residence time≥7 days were all risk fators to lower respiratory tract infection for children with tracheobronchial foreign bodies.Monitoring these risk factors could
作者
周佩佩
吴亚楠
王莹
王然
Zhou Peipei;Wu Yanan;Wang Ying;Wang Ran(Department of Infectious Diseases,Xuzhou Children’s Hospital Affiliated to Xuzhou Medical University,Xuzhou 221006,China;Nursing Department,Xuzhou Children’s Hospital Affiliated to Xuzhou Medical University,Xuzhou 221006,China)
出处
《中华实验和临床感染病杂志（电子版）》
CAS
2021年第4期276-280,共5页
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
基金
江苏省卫生计生委2017年医学科研课题面上项目(No.H201758)。
关键词
气管支气管异物
儿童
下呼吸道感染
危险因素
Tracheobronchial foreign body
Children
Lower respiratory tract infection
Risk factor
