摘要
目的 分析纳布啡加丙泊酚在无痛门诊中的优势。方法 研究对40例无痛人流患者进行了观察,患者于2018年4月至2020年5月在湛江市第二中医医院接受治疗,计算机随机分组方式将其分成对照组和观察组,分别采取舒芬太尼+丙泊酚麻醉和纳布啡+丙泊酚麻醉,比较两组麻醉效果、不良反应和血清炎症因子水平。结果 观察组麻醉起效时间(2.76±1.09)min,麻醉苏醒时间(9.43±0.37)min,丙泊酚用量(101.47±13.28)mg,VAS评分是(1.12±0.27)分,低于对照组,P<0.05;观察组不良反应发生率为5%(1例),比对照组低,P<0.05;观察组术后3h IL-6是(17.83±2.63)ng/L,hs-CRP是(2.87±0.47)mg/L,比对照组低,P<0.05。结论 纳布啡加丙泊酚用于无痛门诊人工流产术麻醉维持和苏醒时间适当,丙泊酚用量低,可减少不良反应,减轻术后炎性反应与疼痛感,安全性较高。
Objective To analyze advantages of nalbuphine and propofol in painless outpatient.Methods The paper chose 40 patients with painless induced abortion treated in painless outpatient department from April 2018 to may 2020 for observation,and divided them into control group and observation group randomly with computer,treated with sufentanil + propofol anesthesia and nalbuphine + propofol anesthesia respectively.Anesthetic effect,adverse reactions and serum inflammatory factor levels between two groups were compared.Results Onset time of anesthesia in observation group was (2.76±1.09) min,anesthesia recovery time (9.43±0.37) min,dosage of propofol was (101.47±13.28) Mg,VAS scores were (1.12±0.27),which were lower than control group,(P<0.05).Incidence of adverse reactions in observation group was 5% (1 case),which was lower than control group,(P<0.05);IL-6 level in observation group was (17.83±2.63) ng/L,hs CRP was (2.87±0.47) mg/L,lower than control group,(P<0.05).Conclusion Nalbuphine and propofol can achieve appropriate anesthesia maintenance and recovery time for painless outpatient abortion,with lower dosage of propofol,less adverse reactions,can reduce postoperative inflammatory reactions and pains,with high safety,it is recommended for clinical promotion.
作者
邓海啸
杨冬婵
DENG Dong-chan;YANG Dong-chan(Department of Anesthesiology,Zlianjiang Qty The Second Hospital of Traditional Chinese Medicine,Zhanjiang,Guangdong,524000)
出处
《智慧健康》
2021年第15期160-162,共3页
Smart Healthcare
关键词
纳布啡
丙泊酚
无痛门诊
人工流产
麻醉效果
不良反应
炎性反应
Naborphine
Propofol
Painless clinic
Induced abortion
Anesthetic effect
Adverse reactions
Inflammatory reaction
