摘要
目的探讨儿童原发性免疫缺陷病(PID)合并结核杆菌(Mtb)感染的胸部CT的特征。方法回顾性分析25例Mtb感染的PID患儿及25例免疫正常的结核病患儿的胸部CT图像。结果PID伴Mtb感染组(A组)肺内病变分布在3叶及以上多于免疫正常结核组(B组)(P<0.01),而局限于1叶少于B组(P<0.05);A组磨玻璃影、网格影及腋窝淋巴结改变多于B组(P<0.05或0.01),A组粟粒性结节、空洞、肺内钙化及胸内淋巴结肿大/钙化/坏死发生情况均少于B组(P<0.05或0.01),而两组在斑片状影、肺实变、结节影、支气管扩张及胸膜病变方面比较,差异均无统计学意义(P>0.05)。结论儿童PID合并Mtb感染的胸部CT表现复杂、多样、不典型,诊断较困难,但仍有一定的特征,应引起重视并需进一步研究。
Objective To explore the chest CT features of children with primary immunodeficiency disease(PID)accompanied by mycobacterium tuberculosis bacillus(Mtb)infection.Methods A retrospective analysis was used on the chest CT images of 25 children with Mtb infection and 25 children with normal immunity.Results The PID group with Mtb infection(group A)had more pulmonary lesions in 3 lobes and above than the immune normal tuberculosis group(group B)(P<0.01),and less in 1 lobe than group B(P<0.05).Ground glass shadow,shadow grid and axillary lymph node changes in group A than in group B(P<0.05 or 0.01).Millet,hollow,the lungs calcification of the nodules and intrathoracic lymph node enlargement/calcium/necrosis group A than group B(P<0.05 or 0.01).And there were no significant differences between two groups of patchy shadow,consolidation of the lung,nodular shadows,bronchiectasis,and pleural lesions(P>0.05).Conclusion The chest CT manifestations of children with PID and Mtb infection are complex,diverse,atypical,and the diagnosis is difficult,but there are still some certain characteristics,which should be paid attention to and further study is needed.
作者
丁浩
张黎
陈欣
何玲
DING Hao;ZHANG Li;CHEN Xin;HE Ling(Radiology Department of Children′s Hospital of Chongqing Medical University,China International Science and Technology Cooperation,Base of Child Development and Critical Disorders,Ministry of Education Key Laboratory of Child Development and Disorders,Chongqing Key Laboratory of Pediatrics,Chongqing 400014,China)
出处
《现代医药卫生》
2021年第18期3070-3073,共4页
Journal of Modern Medicine & Health
基金
重庆市卫生健康委员会科卫联合医学科研项目(2020FYYX128)
重庆市渝中区科技局基金项目(20200155)。
