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观察体外反搏治疗平板运动试验阳性更年期女性胸痛的临床疗效

An Observation of the Clinical Effect of External Counterpulsation on Chest Pain in Menopausal Women with Positive Treadmill Exercise Test
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摘要 目的:观察对平板运动试验阳性更年期女性胸痛采取体外反搏治疗的临床疗效。方法:将2020年1月至2021年1月收治的胸痛患者64例纳入本研究,均处于更年期,且平板运动试验结果均为阳性,数字随机法均分成两组,各32例,其中对照组采取常规药物治疗,观察组采取体外反搏治疗,比较两组临床疗效。结果:观察组总有效率为96.9%,明显高于对照组78.1%(P<0.05);两组治疗前平板运动试验相关数据比较差异无统计学意义(P>0.05),治疗后观察组与治疗前相比其ST段下移幅度减少,ST段出现时间延长且运动耐量提升(P<0.05),而对照组仅ST段下移幅度与治疗前比较差异有统计学意义(P<0.05);治疗后观察组上述指标均明显优于对照组(P<0.05);两组治疗前NO、VEGF及SOD评分比较差异无统计学意义(P>0.05),治疗后两组NO、SOD水平均高于同组治疗前,VEGF水平均低于同组治疗前(P<0.05);治疗后观察组VEGF水平低于对照组,NO、SOD比对照组更高(P<0.05)。结论:ECP治疗平板运动试验阳性更年期女性胸痛临床疗效显著,值得推广。 Objective:To observe the clinical effect of external counterpulsation on the chest pain of menopausal women with positive exercise test.Methods:Sixty-four patients with chest pain admitted from January 2020 to January 2021 were included in this study,all in menopause,and the results of treadmill exercise test were positive.They were divided into two groups by digital random method,with 32 patients in each group.The control group was treated with conventional drug therapy,and the observation group was treated with external counterpulsation.Results:The total effective rate of observation group was 96.9%,which was significantly higher than that of control group(78.1%,P<0.05).Exercising treadmill test data comparison before treatment has no statistical significance(P>0.05).Compared with before treatment,ST segment of the observation group has decreaseed amplitude,ST segment is prolonged and exercise tolerance is elevated(P<0.05),while decreaseed amplitude of ST segment in the control group is statistically significant compared with before treatment(P<0.05).After treatment,the above indexes in observation group were significantly better than those in control group(P<0.05).There were NO significant differences in NO,VEGF and SOD scores between the two groups before treatment(P>0.05).After treatment,NO and SOD levels in the two groups were higher and VEGF levels were lower than before treatment(P<0.05).After treatment,the level of VEGF in observation group was lower than that in control group,and the levels of NO and SOD were higher than those in control group(P<0.05).Conclusion:The clinical effect of ECP in the treatment of menopausal women with positive treadmill exercise test for chest pain is significant,which is worthy of promotion.
作者 刘蕾 许宏伟 姚艳影 宋智勇 罗东雷 LIU Lei;XU Hongwei;YAO Yanying(Chengde Central Hospital,Hebei Chengde 067000,China)
出处 《河北医学》 CAS 2021年第9期1545-1548,共4页 Hebei Medicine
基金 河北省医学科学研究课题计划,(编号:20200236,20200348)。
关键词 体外反搏 平板运动试验阳性 更年期 胸痛 External counterpulsation Positive treadmill exercise test Menopause Chest pain
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