摘要
目的:研究地西他滨联合CAG治疗老年急性髓系白血病的疗效。方法:2018年6月-2020年1月收治老年急性髓系白血病患者84例,随机分为两组,各42例。对照组采取CAG方案治疗,观察组采用CAG+地西他滨治疗,比较两组治疗效果。结果:观察组疾病缓解率高于对照组,死亡率低于对照组,差异均有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:采用CAG方案联合地西他滨治疗老年急性髓系白血病患者,可提高疗效,安全性好,降低患者死亡率。
Objective:To study the efficacy of decitabine combined with CAG in the treatment of elderly patients with acute myeloid leukemia.Methods:From June 2018 to January 2020,84 elderly patients with acute myeloid leukemia were selected,they were randomly divided into the two groups with 42 cases in each group.The control group was treated with CAG regimen.The observation group was treated with CAG and decitabine.We compared the treatment effects of the two groups.Results:The disease remission rate of the observation group was higher than that of the control group,the mortality rate was lower than that of the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions between the two groups was not statistically significant(P>0.05).Conclusion:The use of CAG regimen combined with decitabine in the treatment of elderly patients with acute myeloid leukemia can improve the efficacy,which has good safety and can reduce the mortality of patients.
作者
张改玲
Zhang Gailing(Department of Hematology,Yanda Ludaopei Hospital of Hebei,Hebei Langfang 065201)
出处
《中国社区医师》
2021年第27期47-48,共2页
Chinese Community Doctors
关键词
地西他滨
CAG
老年
急性
髓系白血病
疗效
疾病缓解
Decitabine
CAG
Elderly
Acute
Myeloid leukemia
Curative effect
Disease remission
