摘要
目的:探讨后疫情时代心理状况测评在接受辅助生殖技术(ART)治疗的不孕症女性患者中的应用价值。方法:采用问卷调查方式,使用广泛性焦虑量表-7(GAD-7)、抑郁症状群量表-9(PHQ-9)、患者健康问卷躯体症状群量表-15(PHQ-15)调查2020年6—11月接受ART治疗的不孕症女性患者的一般情况、焦虑情绪、抑郁症状和躯体症状等身心健康状况。信度分析采用克郎巴哈α(Cronbach′sα)系数、Spearman-Brown折半系数和2周后重测信度。结构效度分析和校标效度分析分别采用验证性因子分析和Spearman相关性分析。然后将3个量表的结果转换为两分类变量(正常和阳性结果)分别作为因变量,以患者自身人口学特征以及不孕症相关临床特征为自变量,行多因素Logistic回归分析(进入标准为单因素分析P<0.1)。结果:研究共纳入1980例患者,问卷回收率89.6%(1980/2210)。PHQ-15、GAD-7和PHQ-9量表的Cronbach′sα系数和KMO值分别为0.805、0.863、0.822和0.871、0.909、0.890,提示3个量表的信度及效度均较好。多因素Logistic回归分析显示:年龄>35岁是患者产生焦虑、抑郁及躯体症状的独立危险因素。大专及以上学历、男方吸烟史为患者产生焦虑症状及抑郁症状等心理问题的独立危险因素。现有1个子女为患者抑郁症状[OR(95%CI)为0.63(0.41~0.97),P=0.034]和躯体症状[OR(95%CI)为0.63(0.42~0.94),P=0.022]的独立保护因素。结论:PHQ-15、GAD-7、PHQ-9量表在评估接受ART治疗女性患者身心健康方面有较好的运用。年龄>35岁、大专及以上学历和丈夫吸烟的患者容易产生焦虑、抑郁或躯体症状,应当引起重视。
Objective:To investigate the application value of psychological status assessment in infertile women who received assisted reproductive technology(ART)in the post-epidemic era of COVID-19.Methods:From June 2020 to November 2020,infertile women who received ART treatment were investigated via the patient health questionnaire scale-15(PHQ-15),generalized anxiety disorder scale-7(GAD-7)and patient health questionnaire scale-9(PHQ-9).The general situation,physical symptoms,anxiety,depression symptoms and other physical and mental health status were evaluated.Cronbach′sαcoefficient,Spearman Brown half-split coefficient and two-week-retest reliability were used for the reliability analysis.Confirmatory factor analysis and Spearman correlation analysis were used to analyze the construct validity and criteria validity,respectively.Then the results of the three scales were converted into dichotomous variable(normal and positive results)as dependent variables.Together with patient′s demographic characteristics and infertility-related clinical characteristics which were added as independent variable into the univariate and multivariate logistic regression analysis,respectively(The entry criteria were P<0.1 in univariate analysis).Results:A total of 1980 patients were included in the study,and the effective recovery rate was 89.6%(1980/2210).The Cronbach′sαcoefficient and KMO value of PHQ-15,GAD-7 and PHQ-9 were 0.805,0.863,0.822 and 0.871,0.909,0.890,respectively.These results suggested that the reliability and validity of the three scales were good.Multivariate logistic regression analysis showed that the age of>35 years was the independent risk factor of anxiety,depression and physical symptoms for infertile women.College degree or above and husband smoking were two independent risk factors of anxiety and depression of infertile women.Owned one child was an independent protective factor for depressive symptoms(OR=0.63,95%CI:0.41-0.97,P=0.034)and somatic symptoms(OR=0.63,95%CI:0.42-0.94,P=0.022).Conclusions:PHQ-15,
作者
王灵嫣
周丹
乐艳
王宇扬
WANG Ling-yan;ZHOU Dan;YUE Yan;WANG Yu-yang(Department of Reproductive Medicine Nursing,West China Second University Hospital,Sichuan University,Key Laboratory of Birth Defects and Related Diseases of Women and Children of Sichuan University,Chengdu 610041,China)
出处
《国际生殖健康／计划生育杂志》
CAS
2021年第5期366-371,共6页
Journal of International Reproductive Health/Family Planning
