摘要
目的分析2017—2019年攀枝花市发病的流感样病例检测结果,为流感防控提供依据。方法利用中国流感监测信息系统导出2017年4月—2020年3月3年攀枝花市流感样病例(ILI)标本的荧光PCR检测及病毒分离结果,并对数据进行分析。结果 3个年度共6 047份标本,阳性1 138份,阳性率为18.82%,其中甲型813份占71.44%,乙型325份占28.56%;依次流行H1N1、H3N2、By、H1N1,H1N1、Bv,Bv和H3N2。3年病毒分离阳性率比较,差异有统计学意义(χ^(2)=38.614,P <0.05);不同年龄段阳性率比较,差异有统计学意义(χ^(2)=525.897,P<0.05),5~<15岁组最高;爆发疫情以学校为主;各型病毒分离率比较,差异有统计学意义(χ^(2)=168.217,P<0.05),By最高,H3N2最低;混合感染者<5岁组多发,培养需≥Ⅱ代;悬浮细胞管分离H3N2病毒效率较高。结论 2017年度流感病毒较活跃,前2个年度H1N1流行间隔时间<1年,H3N2分离率低,学校仍为流感防控重点单位,应加强宣传,提高流感疫苗接种率。
Objective To analyze the detection results of influenza-like illness(ILI) cases in Panzhihua City from 2017-2019,provide basis for the prevention and control of influenza. Methods Fluorescence PCR detection and virus isolation results of ILI specimens in Panzhihua City from April 2017 to March 2020 were derived from the China Influenza Surveillance and Information System,and the data were analyzed. Results Among the 6 047 samples in three years,1 138 were positive,with a positive rate of18.82%. Among them,there were 813 cases of influenza A and 325 cases of influenza B,accounting for 71.44% and 28.56%respectively. H1 N1,H3 N2,By and H1 N1 in 2017,H1 N1 and Bv in 2018,Bv and H3 N2 in 2019 were prevalent in turn. There were statistically significant differences in the virus positive rate among the three years (χ^(2)=38.614,P<0.05).There were statistically significant differences in positive rate among different age groups (χ^(2)=525.897,P<0.05),that in 5-<15 year-old age group was the highest,and the outbreaks mainly occurre d in schools. The difference in isolation rate was statistically significant among virus of different types(χ^(2)= 168.217,P<0.05),with the highest in By and the lowest in H3 N2. The mixed infection occurred frequently in the <5 year-old age group,and virus culture need to be greater than or equal to Ⅱ generation. The isolation of H3 N2 virus by suspension cell tube was more efficient. Conclusion Influenza virus are more active in 2017. The interval of H1 N1 epidemic of the past two years is less than 1 year,and the isolation rate of H3 N2 is low. Schools are still the key units for influenza prevention and control,and it is necessary to strengthen publicity to improve influenza vaccination rate.
作者
周霞
吴万里
胡澜怀
杨志敏
李琴
夜富平
ZHOU Xia;WU Wan-li;HU Lan-huai;YANG Zhi-min;LI Qin;YE Fu-ping(Laboratory Department of Panzhihua Center for Disease Control and Prevention,Panzhihua Sichuan,617000,China)
出处
《职业与健康》
CAS
2021年第14期1925-1928,共4页
Occupation and Health
