摘要
目的:探讨新型Nd:YAG分数双波长皮秒激光联合新型全息分束器治疗面部痤疮瘢痕的有效性和安全性。方法:收集2018年1月-2019年9月笔者医院治疗的62例面部痤疮瘢痕患者为研究对象。采用自体对照的方式,左面颊为对照组,右面颊为观察组。对照组给予点阵CO2激光治疗,观察组给予新型Nd:YAG分数双波长皮秒激光联合新型全息分束器治疗。两组均每月治疗1次,共4次。治疗结束12周,评估临床疗效及患者治疗满意度。记录治疗及随访期间的治疗相关不良事件发生情况,对所有数据进行统计学分析。结果:两组临床疗效整体分级间差异具有统计学意义(P<0.05)。观察组总有效率与极有效率均高于对照组(P<0.05)。观察组无效率及弱效率均低于对照组(P<0.05)。观察组治疗满意度评分高于对照组(P<0.05)。观察组红斑、水疱、瘙痒、疼痛、脱屑、色素沉着及色素减退等治疗相关不良事件发生率均低于对照组(均P<0.05)。结论:新型分数双波长皮秒激光联合新型全息分束器治疗面部痤疮瘢痕有效、安全,患者治疗满意度高。
Objective To learn the clinical efficacy and safety analysis of a new Nd:YAG fractional dual-wavelength picosecond laser combined with a new holographic beam splitter in the treatment of atrophy facial acne scars.Methods 62 patients with facial acne scars,treated in our hospital from January 2018 to September 2019,were collected.The autologous control method was adopted.left cheek was taken as control group,while the right cheek was taken as observation group.The control group was given fractional CO2 laser treatment,the observation group was given a new Nd:YAG fractional dual-wavelength picosecond laser combined with a new holographic beam splitter.Both groups were treated once a month for 4 times.Clinical efficacy and patient satisfaction were assessed at 12 weeks after treatment.Record the treatment-related adverse events during treatment and follow-up.Statistical analysis was performed.Results There was a significant difference between two groups in overall clinical efficacy(P<0.05).The total effective rate and extremely effective rate in observation group were higher than those in control group(P<0.05).The ineffective rate and weak effective rate in observation group were lower than those in control group(P<0.05).Patients’treatment satisfaction in observation group was higher than that in control group(P<0.05).The incidence of treatment-related adverse events such as erythema,blistering,itching,pain,desquamation,hyperpigmentation,and hypopigmentation in observation group were lower than those in control group(P<0.05).Conclusion The novel fractional dual-wavelength picosecond laser combined with a new holographic beam splitter is effective and safe for treating atrophy facial acne scars,with high patient's treatment satisfaction.
作者
刘春保
赵彧
关吉利
孔珍珍
LIU Chun-bao;ZHAO Yu;GUAN Ji-li;KONG Zhen-zhen(Department of Dermatology,Sanya Hospital of Traditional Chinese Medicine,Sanya 572000,Hainan,China;Department of Plastic Surgery,Sanya Hospital of Traditional Chinese Medicine,Sanya 572000,Hainan,China)
出处
《中国美容医学》
CAS
2021年第8期83-86,共4页
Chinese Journal of Aesthetic Medicine
关键词
皮秒激光
全息分束器
痤疮瘢痕
疗效
安全性
picosecond laser
holographic beam splitter
acne scars
efficacy
safety
