摘要
目的应用CT血管造影(CTA)分析冠状动脉左主干分支左前降支(LAD)与左回旋支(LCX)夹角度数与斑块特性之间潜在的关联性。方法收集2015年6月~2018年6月因胸痛就诊于华北理工大学附属医院并行冠状动脉CTA患者325例,依据左主干分支夹角度数将患者分组:A组左主干分支夹角<70°108例、B组70°~80°112例、C组>80°105例。采用方差分析及卡方检验比较各组患者斑块特性的差异,左主干夹角度数与斑块CT值的相关性采用Pearson相关分析。结果三组比较左主干分支斑块发生率差异有统计学意义(P<0.05),且随着夹角度数的增加斑块发生率逐步升高。C组不稳定性斑块占比、左主干分支狭窄程度与A组、B组比较,差异均有统计学意义(P<0.05),说明左主干分支夹角度数>80°时,不稳定性斑块占比明显增加、分支狭窄程度明显加重。三组患者左主干分支夹角度数同分支斑块CT值呈负相关(LAD相关系数为-0.514、LCX相关系数为-0.51),左前降支95%置信区间为(-0.561,-0.463),左回旋支95%置信区间为(-0.557,-0.458)。结论CTA可以无创、客观评价左冠状动脉分支夹角与其分支斑块特性的相关性,左主干分支夹角对其分支斑块的特性具有重要影响。
Objective To analyze the relationship about plaques forming in two branches of left coronary artery and left coronary bifurcation angle.Methods To collected 325 patients who had pectoralgia in the hospital where he works.According to their left coronary bifurcation angle(<70°、70°-80°、>80°),divided them into three groups,group A has 108 patients,group B has 112 patients,group C has 105 patients,and tried to find the difference about statistics among every group.Results The differences of incidence rate among three groups was existed(P<0.05),with the increase of angle degree,the incidence of plaque increased gradually.The proportion of unstable plaque in group C was significantly higher than that in group A and group B(P<0.05).It showed that the angle degree of left main branch was more than 80°,the proportion of unstable plaque increased significantly.The stenosis degree of left main branch in group C was significantly different from that in group A and group B(P<0.05).It showed that the angle degree of left main branch was more than 80°,the degree of stenosis of the branches increased significantly.The stenosis degree of left main branch in group C was significantly different from that in group A and group B(P<0.05),It showed that the angle degree of left main branch was more than 80°,the degree of stenosis of the branches increased significantly.There was a negative correlation between the degree of left main branch angle and the CT value of branch plaque(LAD correlation coefficient was-0.514,LCX correlation coefficient was-0.51).The 95% confidence interval of lad was(-0.561,-0.463),The 95% confidence interval of LCX was(-0.557,-0.458).Conclusion The larger the angle degree of left main branch,the incidence of plaque,the proportion of unstable plaque and the degree of vascular stenosis increased,and the angle degree was negatively correlated with the CT value of plaque.
作者
张玄星
陈伟彬
ZHANG Xuanxing;CHEN Weibin(North China University of Science and Technology Affiliated Hospital,Tangshan 063000,China)
出处
《华北理工大学学报（医学版）》
2021年第5期374-379,384,共7页
Journal of North China University of Science and Technology：Health Sciences Edition
关键词
CTA
冠状动脉分支
夹角
斑块
CTA.Coronary artery branch
Included angle
Plaque
