摘要
目的研究异位妊娠(EP)保守治疗患者行米非司酮+甲氨蝶呤治疗效果。方法选择2016年1月—2018年12月该院收治的50例符合保守治疗的EP患者,以随机数字表法分观察组(米非司酮+甲氨蝶呤)与对照组(甲氨蝶呤)各25例,比较两组临床指标、症状恢复时间、临床疗效及不良反应。结果治疗后与对照组比较,观察组β-HCG值较低、包块直径较小;β-HCG恢复、黄体酮恢复及包块消失时间较短,差异有统计学意义;观察组有效率(100.00%)高于对照组(76.00%),差异有统计学意义(χ^(2)=4.735,P=0.030)。结论米非司酮+甲氨蝶呤治疗符合保守治疗的EP患者能提高整体疗效、稳定病情,值得推崇。
Objective To study the effect of mifepristone and methotrexate in conservatively treated patients with ectopic pregnancy(EP).Methods Januany 2016 to December 2018,50 cases of EP patients who were eligible for conservative treatment were selected in the hospital.The random number table method was divided into observation group(mifepristone+methotrexate)and control group(methotrexate)with 25 cases each.Comparison of clinical indicators,symptom recovery time,clinical efficacy and adverse reactions between the two groups.Results After treatment,compared with the control group,the observation group had lowerβ-HCG value and smaller mass diameter;β-HCG recovery,progesterone recovery and mass disappearance time was shorter,the difference was statistically significant(P<0.05);the effective rate of the observation group(100.00%)was higher than that of the control group(76.00%),the difference was statistically significant(χ^(2)=4.735,P=0.030).Conclusion Mifepristone+methotrexate therapy for EP patients who meet conservative treatment can improve the overall efficacy and stabilize the disease,which is worthy of praise.
作者
胡玉媛
HU Yuyuan(Department of Obstetrics and Gynecology,Fenjinting Hospital,Sihong County,Suqian,Jiangsu Province,223900 China)
出处
《系统医学》
2021年第12期136-138,共3页
Systems Medicine
关键词
异位妊娠
米非司酮
甲氨蝶呤
治疗效果
Ectopic pregnancy
Mifepristone
Methotrexate
Therapeutic effect
