摘要
冠状动脉微血管功能障碍是导致心肌缺血的潜在原因,与不良心血管结局相关。目前评价冠状动脉微血管功能障碍的方法包括侵入性冠状动脉微血管功能检测以及心肌声学造影、心脏磁共振等非侵入性检查,但受价格、技术等因素的影响,未能广泛使用。相比而言,一些生物标志物不仅易获取,成本低,而且极大程度地减轻了对患者的损伤,为门诊以及住院部冠状动脉微血管功能障碍患者的管理提供了较为理想的选择。现已发现多种生物标志物在微血管疾病的管理中具有潜在的应用价值,本文就冠状动脉微血管功能障碍生物标志物的研究进展作一综述。
Coronary microvascular dysfunction is a potential cause of myocardial ischemia and is related to adverse cardiovascular outcomes.At present,the methods to evaluate coronary microvascular dysfunction include invasive coronary microvascular function detection,myocardial contrast echocardiography,cardiac magnetic resonance imaging and other non-invasive examination,which are not widely used due to the factors of price,technology,and so on.In contrast,some biomarkers are not only easy to obtain,low in cost,but also greatly reduce the damage to patients,providing an ideal choice for the management of patients with coronary microvascular dysfunction in outpatient and inpatient departments.A variety of biomarkers have been found to have potential application value in the management of microvascular disease.This article reviews the research progress of biomarkers for coronary microvascular dysfunction.
作者
杨军芬
臧雁翔
刘广忠(综述)
李为民(审校)
YANG Junfen;ZANG Yanxiang;LIU Guangzhong;LI Weimin(Department of Cardiology,First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)
出处
《临床与病理杂志》
CAS
2021年第8期1932-1939,共8页
Journal of Clinical and Pathological Research
