摘要
目的探讨全身免疫炎症指数(SII)、血小板/淋巴细胞比值(PLR)、淋巴细胞/单核细胞比值(LMR)及中性粒细胞/淋巴细胞比值(NLR)在不同类型血流感染中的鉴别诊断价值。方法选取该院收治的血流感染患者284例为研究对象,根据血培养结果将患者分为革兰阳性(G^(+))菌组(n=113)和革兰阴性(G^(-))菌组(n=171)。另外选取同期该院50例体检健康者作为对照组。比较G^(+)菌组、G^(-)菌组与对照组患者的NLR、PLR、LMR、SII,并通过受试者工作特征曲线评价4项指标对不同类型血流感染的鉴别诊断价值。结果G^(+)菌组与G^(-)菌组的NLR、PLR及SII明显高于对照组,LMR低于对照组,差异均有统计学意义(P<0.05);G^(-)菌组的NLR、SII高于G^(+)菌组,差异均有统计学意义(P<0.05)。结论炎性反应指标NLR、PLR、LMR、SII对血流感染有较高的诊断价值,其中NLR与SII对不同类型的血流感染患者有一定的鉴别诊断意义。
Objective To explore the differential diagnostic significance of systemic immune-inflammation index(SII),platelet-lymphocyte ratio(PLR),lymphocyte-monocyte ratio(LMR)and neutrophil-lymphocyte ratio(NLR)in different types of bloodstream infections.Methods A total of 284 patients with bloodstream infections were selected in this study and divided into Gram positive(G^(+))bacteria group(n=113)and Gram negative(G^(-))bacteria group(n=171),and another 50 healthy people were selected as control group.Compare NLR,PLR,LMR and SII among the three groups,and evaluate the differential diagnosis value of different types of bloodstream infections by receiver operating characteristic curve.Results The NLR,PLR and SII in G^(+)bacteria group and G^(-)bacteria group were significantly higher than those in control group,and the LMR was lower than that in control group,the differences were statistically significant(P<0.05).The NLR and SII in G^(-)bacteria group were higher than those in G^(+)bacteria group,the differences were statistically significant(P<0.05).Conclusion Inflammation indicators NLR,PLR,LMR and SII have high diagnostic value for bloodstream infections.Among them,NLR and SII have specific differential diagnosis significance for patients with different types of bloodstream infections.
作者
邹小红
凌利芬
刘小晴
李振华
陆学东
ZOU Xiaohong;LING Lifen;LIU Xiaoqing;LI Zhenhua;LU Xuedong(Department of Clinical Laboratory,the Eighth Affiliated Hospital,Sun Yat-sen University,Shenzhen,Guangdong 518033,China;Central Laboratory,the Eighth Affiliated Hospital,Sun Yat-sen University,Shenzhen,Guangdong 518033,China)
出处
《检验医学与临床》
CAS
2021年第17期2501-2503,共3页
Laboratory Medicine and Clinic
基金
广东省深圳市福田区科技项目(FTWS2018046)。
关键词
中性粒细胞/淋巴细胞比值
全身免疫炎症指数
血流感染
鉴别诊断
neutrophil-lymphocyte ratio
systemic immune-inflammation index
bloodstream infection
differential diagnosis
