摘要
目的分析某油田职工健康体检人群结直肠腺瘤息肉患病情况及临床特征。方法选择2017年1月—2018年12月在我院体检并进行结肠镜检查的河北省华北油田地区职工2000例,根据肠镜检查结果分为结直肠腺瘤息肉组(观察组)与对照组,比较两组一般资料,并分析结直肠腺瘤息肉病人临床与病理特征及其发病的危险因素。结果2000例受检者中腺瘤性息肉检出312例(15.60%)。40岁以上腺瘤息肉检出率(17.96%)显著高于40岁以下人群(2.88%),差异具有统计学意义(χ^(2)=45.633,P<0.001)。观察组的男性、年龄、体质量指数(BMI)、有吸烟史和饮酒史、有家族史者、三酰甘油(TG)、总胆固醇(TC)、幽门螺杆菌(Hp)阳性率等均高于对照组(t=2.183~17.088,χ^(2)=24.692~338.736,P<0.05)。观察组共检出腺瘤性息肉431枚,本组的临床表现和病理特征有其特点。Logistic回归模型多因素分析显示,男性、>50岁、TG>2.5 mmol/L、有吸烟史、有家族史等是发病的独立危险因素(OR=1.431~3.167,95%CI=1.140~7.868,P<0.05)。结论结直肠腺瘤息肉的发病呈年轻化趋势,其发病与性别、年龄、高TG血症、吸烟史与结直肠息肉及结直肠癌家族史等有关。
Objective To investigate the prevalence and clinical features of colorectal adenomatous polyps in oilfield workers undergoing physical examination.Methods A total of 2000 workers from Huabei Oilfield of Hebei Province who underwent physical examination and colonoscopy in our hospital from January 2017 to December 2018 were enrolled,and according to the results of colonoscopy,they were divided into colorectal adenomatous polyp group(observation group)and control group.Ge-neral data was compared between the two groups,and clinicopathological characteristics and risk factors were analyzed for patients with colorectal adenomatous polyps.Results Among the 2000 workers,312(15.60%)had adenomatous polyps.The workers aged 40 years or older had a significantly higher detection rate of adenomatous polyps than those aged<40 years(17.96%vs 2.88%,χ^(2)=45.633,P<0.001).Compared with the control group,the observation group had significantly higher proportion of male workers,age,body mass index,proportion of workers with smoking history/drinking history/family history,levels of triglycerides(TG)and total cholesterol,positive rate of Helicobacter pylori(t=2.183-17.088,χ^(2)=24.692-338.736,P<0.05).A total of 431 adenomatous polyps were detected in the observation group,and this disease had unique clinical manifestations and pathological features.The multivariate logistic regression analysis showed that male sex,age>50 years,TG>2.5 mmol/L,smo-king history,and family history were independent risk factors for this disease(OR=1.431-3.167,95%CI=1.140-7.868,P<0.05).Conclusion The onset age of colorectal adenomatous polyps tends to become younger,and the development of this disease is associated with sex,age,hypertriglyceridemia,smoking history,family history of colorectal polyps and colorectal cancer.
作者
陈策
刘复娜
董云峰
郭凤霞
刘小娟
张红丽
CHEN Ce;LIU Funa;DONG Yunfeng;GUO Fengxia;LIU Xiaojuan;ZHANG Hongli(Department of Gastroenterology,Huabei Petroleum Administration Bureau General Hospital,Renqiu 062550,China)
出处
《青岛大学学报（医学版）》
2021年第4期605-608,共4页
Journal of Qingdao University(Medical Sciences)
基金
河北省医学研究课题计划项目(20191167)。
关键词
结直肠腺瘤息肉
健康调查
临床特征
危险因素
colorectal adenomatous polyps
health survey
clinical features
risk factors
