摘要
阴道毛滴虫是一种有鞭毛的寄生原虫,是世界上最常见的性传播病原体之一。女性感染后阴道毛滴虫多寄生于阴道,导致滴虫性阴道炎。阴道毛滴虫也可感染男性,男性感染后虫体可经泌尿生殖道逆行至膀胱、前列腺、精囊、睾丸、附睾等组织,对精子细胞或其他组织造成严重损伤,引起尿道炎、前列腺炎、前列腺癌、弱精或无精,进而影响男性的生育能力。由于男性感染的临床症状较轻或无临床症状,因此常常被忽视。本文就近年来男性感染阴道毛滴虫造成精子、睾丸以及前列腺功能异常,进而导致男性不育的相关机制作一综述。
Trichomonas vaginalis is a type of flagellated protozoan and the most common sexually transmitted pathogens in the world.T.vaginalis mainly parasitizes in the female vagina,leading to trichomonal vaginitis.In addition,T.vaginalis can also infect males,and the parasites may retrograde to the bladder,prostate,seminal vesicle,testis,epididymis and other tissues,through the urogenital tract,thus causing serious damage to sperm cells or other tissues;causing urethritis,prostatitis,prostate cancer,asthenospermia or azoospermia,eventually affecting the male fertility.However,T.vaginalis infection in males often presents mild or no clinical symptoms,resulting in ignorance of the infection.In this paper,we review the related mechanisms underlying the T.vaginalis infection-induced abnormal sperm,testicular and prostate functions,and thereby male infertility.
作者
段玉娟
李朋举
桑雨慧
吴璞成
商雨佳
郝利霞
王帅
李祥瑞
张振超
DUAN Yu-juan;LI Peng-ju;SANG Yu-hui;WU Pu-cheng;SHANG Yu-jia;HAO Li-xia;WANG Shuai;LI Xiang-rui;ZHANG Zhen-chao(School of Basic Medical Sciences,Xinxiang Medical University,Xinxiang 453003,China;Xinxiang Key Laboratory of Pathogenic Biology,Xinxiang Medical University,Xinxiang 453003,China;Xinxiang Maternity and Child Health Care Hospital,Xinxiang 453003,China;College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China)
出处
《中国寄生虫学与寄生虫病杂志》
CSCD
北大核心
2021年第4期532-536,共5页
Chinese Journal of Parasitology and Parasitic Diseases
基金
国家自然科学基金(81802028)
新乡医学院博士科研启动基金(XYBSKZZ201631)
新乡市科技攻关计划项目(GG2019034)。
关键词
阴道毛滴虫
不育
精子
前列腺
睾丸
Trichomonas vaginalis
Infertility
Sperm
Prostate
Testicles
