摘要
视神经脊髓炎谱系疾病(neuromyelitis optica spectrum disorders,NMOSD)是一组主要由体液免疫参与的抗原-抗体介导的中枢神经系统炎性脱髓鞘疾病谱。利妥昔单抗(rituximab,RTX)可用于NMOSD的预防、一线治疗及抢救治疗,能显著降低复发率,改善残疾,安全性较高。本文综述了RTX治疗NMOSD的国内外用药方案,为临床用药提供参考。
Neuromyelitis optica spectrum disorder(NMOSD)is an antigen-antibody-mediated inflammatory demyelination disease spectrum of the central nervous system,which is mainly involved in humoral immunity.Rituximab(RTX)used in the prevention and first-line emergency treatment of NMOSD can significantly reduce recurrent and disability rates of patients,with good safety.This paper reviewed the domestic and foreign medication regimens of RTX in the treatment of NMOSD,so as to provide reference for clinical medication of the drug.
作者
汤迎爽
王津存
关月
乔逸
王磊
康阿龙
TANG Yingshuang;WANG Jincun;GUAN Yue;QIAO Yi;WANG Lei;KANG Along(Department of Pharmacy,First Affiliated Hospital of Air Force Military Medical University,Xi’an 710032,China;Department of Neurology,First Affiliated Hospital of Air Force Military Medical University,Xi’an 710032,China)
出处
《药学服务与研究》
CAS
2021年第4期298-300,共3页
Pharmaceutical Care and Research
