摘要
耐药是癌症治疗面临的主要难题,明确肿瘤耐药机制和寻找新的药物靶点有重要的临床意义。多组学主要包括基因组学、表观基因组学、转录组学、蛋白质组学、代谢组学、影像组学等。近年来,肿瘤耐药研究从单组学到多组学联合,取得了飞速的发展,显著加快了肿瘤新的药物靶点的发现。
Drug resistance is the main obstacle in the treatment of many cancers.It is of great clinical significance to study the mechanism of drug resistance and find new targets.Multi-omics mainly includes genomics,epigenomics,transcriptomics,proteomics,metabolomics,and radiomics.In recent years,the research of tumor resistance has made rapid development,which has significantly accelerated the discovery of new targets.
作者
孙泽恩
刘玉洁
欧阳倩颖
刘昭前
刘英姿
SUN Ze’en;LIU Yujie;OUYANG Qianying;LIU Zhaoqian;LIU Yingzi(Department of Clinical Pharmacology,Xiangya Hospital,Central South University,Changsha 410008;Institute of Clinical Pharmacology,Central South University,Hunan Key Laboratory of Pharmacogenetics,Changsha 410078,China)
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2021年第6期620-627,共8页
Journal of Central South University ：Medical Science
基金
国家自然科学基金(81974512)。
