摘要
For decades,chronic liver disease has remained an increasing global health threat.Despite vaccines and antiviral therapies,both hepatitis B and C remain enormous clinical problems.Hepatic steatosis has become a rapidly increasing worldwide concern that can be appropriately characterized as an evolving epidemic.1 Aroundtheworld alcohol consumption is onthe rise,while autoim-mune conditions and environmental toxins all continue contrib-uting to this seemingly universal health dilemma.The common denominator of chronic liver disease is progressive hepatic inflam-mation leading to fibrosis and cirrhosis.
基金
This manuscript is supported by grants funded by the USA Na-tional Institutes of Health U01CA179582 and R01CA222490.
